Evidence map›Paper›PMID 17855673›Full record

ReviewThe New England journal of medicine2007

Myocardial reperfusion injury.

Derek M Yellon, Derek J Hausenloy

8 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in The New England journal of medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 1,602 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,602citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02286544 phase1completedstarted 2014, after this paper: background citation

Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Single Center, Randomized, Controlled Pilot Study in Healthy Volunteers

Ran2014Enrolled36Registered outcomes1Posted comparisons0ConditionsAcute Coronary Syndrome (ACS), Inflammation, Myocardial Infarction, Reperfusion InjuryArmsAtorvastatin, Oxygen (Oxymask®), Salmonella typhi vaccine (Typhim Vi®)
Open the trial in the graph
NCT01113008 nacompletednot on this mapstarted 2009, after this paper: background citation

Remote Ischemic Postconditioning. Can it Prevent Myocardial Injury During Percutaneous Coronary Intervention?

TypeinterventionalSponsorHospital Universitario Virgen de la VictoriaRan2009 to 2012Enrolled266ConditionsMyocardial Reperfusion InjuryArmsRemote ischemic postconditioning, Control group
NCT02290080 phase3completednot on this mapstarted 2014, after this paper: background citation

Determination of the Role of Oxygen on Mechanisms Involved in Ischemia-reperfusion Injury in Suspected Acute Myocardial Infarction by Biomarkers. A Sub Study to the DETO2X-AMI Trial.

TypeinterventionalSponsorKarolinska InstitutetRan2014 to 2015Enrolled175ConditionsAcute Myocardial Infarction (AMI), Acute Coronary Syndrome (ACS), ST Elevation (STEMI) Myocardial Infarction, Ischemic Reperfusion InjuryArmsOxygen
NCT02313961 nacompletednot on this mapstarted 2013, after this paper: background citation

Evaluation of Remote Ischemic Conditioning in ST-elevation Myocardial Infarction as Adjuvant to Primary Angioplasty

TypeinterventionalSponsorHospital de BragaRan2013 to 2018Enrolled516ConditionsST Elevation Myocardial InfarctionArmsRemote ischaemic conditioning
NCT02981680 nacompletednot on this mapstarted 2013, after this paper: background citation

Effect of Remote Ischemic Preconditioning on the Incidence of Acute Kidney Injury in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Randomized Controlled Trial

TypeinterventionalSponsorShiraz University of Medical SciencesRan2013 to 2017Enrolled180ConditionsAcute Kidney Injury, Coronary Artery Bypass, Ischemic PreconditioningArmsRemote Ischemic Preconditioning (RIPC), sham-RIPC
NCT03004703 phase2completednot on this mapstarted 2017, after this paper: background citation

ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial

TypeinterventionalSponsorOslo University HospitalRan2017 to 2021Enrolled200ConditionsCoronary Disease, Myocardial InfarctionArmsTocilizumab, Sodium chloride 0.9%
NCT03022877 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

Acute and Chronic Protective Effects of Peri-interventional Administration of Levosimendan in ST Elevation Myocardial Infarctions

TypeinterventionalSponsorRWTH Aachen UniversityRan2017 to 2018Enrolled0ConditionsMyocardial Infarction, OutcomeArmsLevosimendan
NCT03995732 phase2unknown statusnot on this mapstarted 2019, after this paper: background citation

Efficacy and Safety Evaluation of Phosphatidyl Choline Cu/Zn Superoxide Dismutase (PC-SOD) for Injection in Reducing Myocardial Reperfusion Injury: a Multicenter, Randomized, Single-blind, Placebo-controlled Dose-finding Study

TypeinterventionalSponsorBeijing Tide Pharmaceutical Co., LtdRan2019 to 2021Enrolled120ConditionsMyocardial Reperfusion InjuryArmsPC-SOD, placebo
3 · Its place in the literature

Who cites it

1,602 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  9. A randomised trial of selective intracoronary hypothermia during primary PCI.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
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1,542 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Derek M YellonHatter Cardiovascular Institute, University College London Hospital and Medical School, London, United Kingdom. hatter-institute@ucl.ac.uk
Derek J Hausenloy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell DeathDisease Models, AnimalHumansIschemic Preconditioning, MyocardialMitochondrial Membrane Transport ProteinsMyocardial InfarctionMyocardial ReperfusionMyocardial Reperfusion InjuryPhosphate Transport ProteinsThrombolytic TherapyMitochondrial Membrane Transport ProteinsPhosphate Transport Proteins

Identifiers

PMID17855673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.