Evidence map›Paper›PMID 17855395›Full record

ArticleNucleic acids research2007

Novel rapidly evolving hominid RNAs bind nuclear factor 90 and display tissue-restricted distribution.

Andrew M Parrott, Michael B Mathews

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
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  6. AbioRxiv : the preprint server for biology · 2024
    Article
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  9. Long Non-Coding RNAs inFrontiers in cellular and infection microbiology · 2022
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  16. The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew M ParrottDepartment of Biochemistry and Molecular Biology, New Jersey Medical School, UMDNJ, 185 South Orange Ave., P. O. Box 1709, Newark, NJ 07101-1709, USA.
Michael B Mathews
Rutgers New Jersey Medical School

Funding

Functions of Double-stranded RNA Binding ProteinsR01AI034552 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI MATHEWS, MICHAEL B · 1993 to 2008
$4.4M
NIAID NIH HHS AI034552NIAID NIH HHS R01 AI034552
6 · The paper itself

Abstract

Nuclear factor 90 (NF90) is a double-stranded RNA-binding protein implicated in multiple cellular functions, but with few identified RNA partners. Using in vivo cross-linking followed by immunoprecipitation, we discovered a family of small NF90-associated RNAs (snaR). These highly structured non-coding RNAs of approximately 117 nucleotides are expressed in immortalized human cell lines of diverse lineages. In human tissues, they are abundant in testis, with minor distribution in brain, placenta and some other organs. Two snaR subsets were isolated from human 293 cells, and additional species were found by bioinformatic analysis. Their genes often occur in multiple copies arranged in two inverted regions of tandem repeats on chromosome 19. snaR-A is transcribed by RNA polymerase III from an intragenic promoter, turns over rapidly, and shares sequence identity with Alu RNA and two potential piRNAs. It interacts with NF90's double-stranded RNA-binding motifs. snaR orthologs are present in chimpanzee but not other mammals, and include genes located in the promoter of two chorionic gonadotropin hormone genes. snaRs appear to have undergone accelerated evolution and differential expansion in the great apes.

Indexed as

Evolution, MolecularAnimalsBase SequenceCell LineHumansMolecular Sequence DataNuclear Factor 90 ProteinsPan troglodytesRNA Polymerase IIIRNA, UntranslatedSequence AlignmentTissue DistributionNuclear Factor 90 ProteinsRNA Polymerase IIIRNA, Untranslated

Identifiers

PMID17855395
PMCPMC2094060
OpenAlexW2048175200

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.