ArticleMolecules (Basel, Switzerland)2007
Preparative separation and identification of the flavonoid phlorhizin from the crude extract of Lithocarpus polystachyus Rehd.
Article in Molecules (Basel, Switzerland), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Via Air or Rhizosphere: The Phytotoxicity ofPlants (Basel, Switzerland) · 2025Review
- Phlorizin, an Important Glucoside: Research Progress on Its Biological Activity and Mechanism.Molecules (Basel, Switzerland) · 2024Review
- Enzymatic Production of 3-OH Phlorizin, a Possible Bioactive Polyphenol from Apples, byAntioxidants (Basel, Switzerland) · 2021Article
- The Bioavailability, Extraction, Biosynthesis and Distribution of Natural Dihydrochalcone: Phloridzin.International journal of molecular sciences · 2021Review
- Synthesis, antioxidant and antimicrobial activity of a new phloridzin derivative for dermo-cosmetic applications.Molecules (Basel, Switzerland) · 2012Article
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Authors and funding
6 authors.
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Abstract
The flavonoid phlorhizin is abundant in the leaves of Sweet Tea (ST, Lithocarpus Polystachyus Rehd). Phlorhizin was preparatively separated and purified from a crude ST extract containing 40% total flavonoids by static adsorption and dynamic desorption on ADS-7 macroporous resin and neutral alumina column chromatography. Only water and ethanol were used as solvents and eluants throughout the whole separation and purification process. Using a phlorhizin standard as the reference compound, the target compound separated from the crude ST extracts was analyzed by thin layer chromatography (TLC), high performance liquid chromatography (HPLC) and electrospray ionization mass spectrometry (EIS-MS) and identified as 99.87% pure (by HPLC-UV) phlorhizin. The results showed that 10 g of the target compound could be obtained from 40 g of the crude extracts in a single operation, indicating a 40% recovery. Therefore, this represents an efficient and environmentally-friendly technology for separating and purifying phlorhizin from ST leaves.
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