ArticleAnalytical and bioanalytical chemistry2008
Characterization of cellular chemical dynamics using combined microfluidic and Raman techniques.
Article in Analytical and bioanalytical chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Discrimination between Carbapenem-Resistant and Carbapenem-Sensitive Klebsiella pneumoniae Strains through Computational Analysis of Surface-Enhanced Raman Spectra: a Pilot Study.Microbiology spectrum · 2022Article
- Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform.The Analyst · 2020Article
- Transport of dynamic biochemical signals in a microfluidic single cell trapping channel with varying cross-sections.The European physical journal. E, Soft matter · 2019Article
- Metabolic characteristics revealing cell differentiation of nasopharyngeal carcinoma by combining NMR spectroscopy with Raman spectroscopy.Cancer cell international · 2019Article
- Nanoparticles and intracellular applications of surface-enhanced Raman spectroscopy.The Analyst · 2016Review
- Raman Spectroscopy of Optically Trapped Single Biological Micro-Particles.Sensors (Basel, Switzerland) · 2015Review
- Optofluidic detection for cellular phenotyping.Lab on a chip · 2012Review
- Metabolic impact of 4-hydroxynonenal on macrophage-like RAW 264.7 function and activation.Chemical research in toxicology · 2012Article
- Gold nanoparticle-based surface-enhanced Raman scattering for noninvasive molecular probing of embryonic stem cell differentiation.PloS one · 2011Article
- SERS nanosensors that report pH of endocytic compartments during FcεRI transit.Analytical and bioanalytical chemistry · 2010Article
- Imaging metabolic syndrome.EMBO molecular medicine · 2010Review
- Surface-enhanced Raman scattering tags for rapid and homogeneous detection of circulating tumor cells in the presence of human whole blood.Journal of the American Chemical Society · 2008Article
- Microfluidic single-cell analysis of intracellular compounds.Journal of the Royal Society, Interface · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The integration of a range of technologies including microfluidics, surface-enhanced Raman scattering and confocal microspectroscopy has been successfully used to characterize in situ single living CHO (Chinese hamster ovary) cells with a high degree of spatial (in three dimensions) and temporal (1 s per spectrum) resolution. Following the introduction of a continuous flow of ionomycin, the real time spectral response from the cell was monitored during the agonist-evoked Ca(2+) flux process. The methodology described has the potential to be used for the study of the cellular dynamics of a range of signalling processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.