ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2008
Bone mineral density in post-menopausal female subjects is associated with serum antioxidant carotenoids.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- The effects of β-carotene on osteoporosis: a systematic review and meta-analysis of observational studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011Trial
- Dietary carotenoid intake and fracture risk based on NHANES 2013-2018 data: a propensity score matching.Journal of health, population, and nutrition · 2025Article
- Clinical features and shared mechanisms of chronic gastritis and osteoporosis.Scientific reports · 2023Article
- Association between Phytochemical Index and Osteoporosis in Women: A Prospective Cohort Study in Korea.Nutrients · 2023Article
- Raman Spectroscopy of Carotenoid Compounds for Clinical Applications-A Review.Molecules (Basel, Switzerland) · 2022Review
- Dietary carotenoid intake and osteoporosis: the National Health and Nutrition Examination Survey, 2005-2018.Archives of osteoporosis · 2021Article
- Association between Serum Uric Acid Levels and Bone Mineral Density in Postmenopausal Women: A Cross-Sectional and Longitudinal Study.Healthcare (Basel, Switzerland) · 2021Article
- The Safe and Effective Use of Plant-Based Diets with Guidelines for Health Professionals.Nutrients · 2021Review
- Orange juice intake and anthropometric changes in children and adolescents.Public health nutrition · 2021Article
- Effects ofFoods (Basel, Switzerland) · 2021Article
- Nutritional Supplements and Skeletal Health.Current osteoporosis reports · 2021Review
- Bone loss, low height, and low weight in different populations and district: a meta-analysis between vegans and non-vegans.Food & nutrition research · 2020Article
- Intrinsic and Extrinsic Factors Impacting Absorption, Metabolism, and Health Effects of Dietary Carotenoids.Advances in nutrition (Bethesda, Md.) · 2018Review
- Article
- Relationship between bone mineral density and dietary intake of β-carotene, vitamin C, zinc and vegetables in postmenopausal Korean women: a cross-sectional study.The Journal of international medical research · 2016Article
- Greater serum carotenoid concentration associated with higher bone mineral density in Chinese adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- Absorption, metabolism, and functions of β-cryptoxanthin.Nutrition reviews · 2016Review
- Association between serum uric acid and bone health in general population: a large and multicentre study.Oncotarget · 2015Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledHigh intake of fruit and vegetables may reduce the risk of osteoporosis. Carotenoids exist in abundance in these foods. This study showed the association of bone mineral density with serum carotenoids. The findings suggest that beta-cryptoxanthin and beta-carotene might provide benefits to bone health in post-menopausal female subjects.
introductionAntioxidant carotenoids are abundant in fruit and vegetables. Recent epidemiological studies show that high intakes of fruit and vegetables may reduce the risk of osteoporosis, but little is known about the association of bone mineral density (BMD) with serum carotenoids.
methodsA total of 699 subjects (222 males and 477 females) who had received health examinations in the town of Mikkabi, Shizuoka Prefecture, Japan, participated in the study. Radial BMD was measured using dual-energy X-ray absorptiometry (DXA). The associations of serum carotenoid concentrations with the radial BMD were evaluated cross-sectionally.
resultsIn male and pre-menopausal female subjects, the six serum carotenoids were not associated with the radial BMD. On the other hand, in post-menopausal female subjects, serum beta-cryptoxanthin and beta-carotene were weakly but positively correlated with the radial BMD. After adjustment for confounders, the odds ratio (OR) for the lowest quartile of BMD in the high groups (Q2-Q4) of serum beta-cryptoxanthin against the lowest quartile (Q1) was 0.45 (95% confidence interval: 0.22-0.95) in post-menopausal female subjects. However, this association was not significant after further adjusting for intakes of minerals and vitamins.
conclusionsAntioxidant carotenoids, especially beta-cryptoxanthin, significantly but partly associate with the radial BMD in post-menopausal female subjects.
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