ArticleJournal of molecular evolution2007
Two paralogous genes encoding small subunits of ADP-glucose pyrophosphorylase in maize, Bt2 and L2, replace the single alternatively spliced gene found in other cereal species.
Article in Journal of molecular evolution, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Sucrose synthases are not involved in starch synthesis in Arabidopsis leaves.Nature plants · 2022Article
- Structure, function, and evolution of plant ADP-glucose pyrophosphorylase.Plant molecular biology · 2022Review
- Functional characterization of a starch synthesis-related genePlant signaling & behavior · 2020Article
- ADP-Glucose Pyrophosphorylase Is Located in the Plastid and Cytosol in the Pulp of Tropical Banana Fruit (Musa acuminata).Plant foods for human nutrition (Dordrecht, Netherlands) · 2020Article
- Cassava AGPase genes and their encoded proteins are different from those of other plants.Planta · 2019Article
- Identification and Expression Analysis of WheatFrontiers in genetics · 2018Article
- Functional Analysis of a Wheat AGPase Plastidial Small Subunit with a Truncated Transit Peptide.Molecules (Basel, Switzerland) · 2017Article
- Comparative Analysis of AGPase Genes and Encoded Proteins in Eight Monocots and Three Dicots with Emphasis on Wheat.Frontiers in plant science · 2017Article
- AGPase: its role in crop productivity with emphasis on heat tolerance in cereals.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Review
- Genome-wide identification of evolutionarily conserved alternative splicing events in flowering plants.Frontiers in bioengineering and biotechnology · 2015Article
- Transcriptome analysis of carbohydrate metabolism during bulblet formation and development in Lilium davidii var. unicolor.BMC plant biology · 2014Article
- Functions of multiple genes encoding ADP-glucose pyrophosphorylase subunits in maize endosperm, embryo, and leaf.Plant physiology · 2014Article
- Chloroplast-localized 6-phosphogluconate dehydrogenase is critical for maize endosperm starch accumulation.Journal of experimental botany · 2013Article
- Maize gene atlas developed by RNA sequencing and comparative evaluation of transcriptomes based on RNA sequencing and microarrays.PloS one · 2013Article
- Article
- Extensive changes to alternative splicing patterns following allopolyploidy in natural and resynthesized polyploids.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Contrasted patterns of selection since maize domestication on duplicated genes encoding a starch pathway enzyme.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Comparison of the starch synthesis genes between maize and rice: copies, chromosome location and expression divergence.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- Proteins from multiple metabolic pathways associate with starch biosynthetic enzymes in high molecular weight complexes: a model for regulation of carbon allocation in maize amyloplasts.Plant physiology · 2009Article
- Transcriptomic analysis of starch biosynthesis in the developing grain of hexaploid wheat.International journal of plant genomics · 2009Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two types of gene encoding small subunits (SSU) of ADP-glucose pyrophosphorylase, a starch-biosynthetic enzyme, have been found in cereals and other grasses. One of these genes encodes two SSU proteins. These are targeted to different subcellular compartments and expressed in different organs of the plant: the endosperm cytosol and the leaf plastids. The SSU gene encoding two proteins evolved from an ancestral gene encoding a single protein by the acquisition of an alternative first exon. Prior to the work reported here, this type of SSU gene had been found in all grasses examined except maize. In maize, two separate genes, Bt2 and L2, were known to have the same roles as the alternatively spliced gene found in other grasses. The evolutionary origin of these maize genes and their relationship to the SSU genes in other grasses were unclear. Here we show that Bt2 and L2 are paralogous genes that arose as a result of the tetraploidization of the maize genome. Both genes derive from an ancestral alternatively spliced SSU gene orthologous to that found in other grasses. Following duplication, the Bt2 and L2 genes diverged in function. Each took a different one of the two functions of the ancestral gene. Now Bt2 encodes the endosperm cytosolic SSU but does not contribute significantly to leaf AGPase activity. Similarly, L2 has lost the use of one of its two alternative first exons. It can no longer contribute to the endosperm cytosolic SSU but is probably responsible for the bulk of the leaf AGPase SSU.
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