ArticleDiabetologia2007
Vibrotactile threshold measurement for detecting peripheral neuropathy: defining variability and a normal range for clinical and research use.
Article in Diabetologia, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Acute Effects of a Whole Body Vibration Session on the Vibration Perception Threshold in Patients with Type 2 Diabetes Mellitus.International journal of environmental research and public health · 2020Trial
- Novel neurosensory testing in cancer patients treated with the epothilone B analog, ixabepilone.Annals of oncology : official journal of the European Society for Medical Oncology · 2008Trial
- Vibration Perception Threshold as a Method for Detecting Diabetic Peripheral Neuropathy: A Systematic Review of Measurement Characteristics.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluation of hand muscle strength, deficiency and hand sensation in individuals with type 2 diabetes.Experimental brain research · 2025Article
- Article
- Assessing the vibration perception threshold in a community sample of adult Ghanaians.PloS one · 2023Article
- Test-Retest Reliability of Vibration Perception Threshold Test in People with Type 2 Diabetes Mellitus.International journal of environmental research and public health · 2020Article
- A Tactile Virtual Reality for the Study of Active Somatosensation.Frontiers in integrative neuroscience · 2020Article
- VSA-3000: A Quantitative Vibration Sensation Testing Device for Patients With Central Nervous System Injury.Frontiers in neurology · 2020Article
- Age-related differences in patient-reported and objective measures of chemotherapy-induced peripheral neuropathy among cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Article
- Phenotypic Characterization of Paclitaxel-Induced Peripheral Neuropathy in Cancer Survivors.Journal of pain and symptom management · 2018Article
- Impact of chemotherapy-induced neurotoxicities on adult cancer survivors' symptom burden and quality of life.Journal of cancer survivorship : research and practice · 2018Article
- Hearing loss and tinnitus in survivors with chemotherapy-induced neuropathy.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2018Article
- Chemotherapy-Induced Neuropathy in Cancer Survivors.Journal of pain and symptom management · 2017Article
- Impairment of color vision in aircraft maintenance workers.International archives of occupational and environmental health · 2011Article
- Age, gender, and side differences of cutaneous electrical perceptual threshold testing in an able-bodied population.The journal of spinal cord medicine · 2010Article
- Chemobrain: a translational challenge for neurotoxicology.Neurotoxicology · 2008Review
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisWe aimed to define normal ranges for vibration sense as measured by vibratory perception thresholds (VPTs) using biothesiometry.
methodsWe performed biothesiometry in a community-dwelling sample of 901 people aged 55 to 85 years who did not have diabetes. We quantitated the variation between repeat measures using analysis of variance and Bland-Altman plots. We also plotted the age- and sex-specific reference ranges.
resultsWe found small but statistically significant differences between repeat measures using the ascending and descending method of limits. Statistically higher vibration thresholds were noted on the right arm and leg compared with the left. Significantly higher vibration thresholds were also seen in men vs women for both lower limbs. We also defined sex-specific reference intervals (normal ranges) for biothesiometry for older persons and quantitated the increase in vibration threshold with increasing age. CONCLUSIONS/
interpretationFor reliability, it may be sufficient to obtain the average of two ascending measures separated by at least 1 min in just the right hand or right foot, since this is usually the one with the higher threshold. Although identical reference ranges can be used for men and women for the upper limb, there are significant differences in the lower limbs. The major determinant of VPT is age: we have established age-specific norms for VPT testing for adults between 55 and 85 years of age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.