ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2007
Use of fluorescent quantum dot bioconjugates for cellular imaging of immune cells, cell organelle labeling, and nanomedicine: surface modification regulates biological function, including cytotoxicity.
Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 97 citations in OpenAlex.
- Recent Advances in Nanodrug Delivery Systems Production, Efficacy, Safety, and Toxicity.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Carbon Nanodots Inhibit Tumor Necrosis Factor-α-Induced Endothelial Inflammation through Scavenging Hydrogen Peroxide and Upregulating Antioxidant Gene Expression in EA.hy926 Endothelial Cells.Antioxidants (Basel, Switzerland) · 2024Article
- Advanced Imaging Techniques for the Characterization of Subcellular Organelle Structure in Pancreatic Islet β Cells.Comprehensive Physiology · 2023Article
- Biomolecular Adsorprion at ZnS Nanomaterials: A Molecular Dynamics Simulation Study of the Adsorption Preferences, Effects of the Surface Curvature and Coating.Nanomaterials (Basel, Switzerland) · 2023Article
- High-quantum yield alloy-typed core/shell CdSeZnS/ZnS quantum dots for bio-applications.Journal of nanobiotechnology · 2022Article
- Anti-Inflammatory Effect and Cellular Uptake Mechanism of Carbon Nanodots in in Human Microvascular Endothelial Cells.Nanomaterials (Basel, Switzerland) · 2021Article
- Quantum Dots for Improved Single-Molecule Localization Microscopy.The journal of physical chemistry. B · 2021Article
- Strategic use of nanotechnology in drug targeting and its consequences on human health: A focused review.Interventional medicine & applied science · 2019Review
- Co-evolution of tumor-associated macrophages and tumor neo-vessels during cervical cancer invasion.Oncology letters · 2016Article
- Non-Cytotoxic Quantum Dot-Chitosan Nanogel Biosensing Probe for Potential Cancer Targeting Agent.Nanomaterials (Basel, Switzerland) · 2015Article
- Smart polymeric nanoparticles for cancer gene delivery.Molecular pharmaceutics · 2015Review
- Impacts of quantum dots in molecular detection and bioimaging of cancer.BioImpacts : BI · 2014Review
- The role of ligand coordination on the cytotoxicity of cationic quantum dots in HeLa cells.Nanoscale · 2013Article
- Evaluation of anti-inflammatory drug-conjugated silicon quantum dots: their cytotoxicity and biological effect.International journal of molecular sciences · 2013Article
- Effect of magnetic nanoparticles on tobacco BY-2 cell suspension culture.International journal of environmental research and public health · 2012Article
- Impact of nanotechnology in cancer: emphasis on nanochemoprevention.International journal of nanomedicine · 2012Review
- Biomimetic, mild chemical synthesis of CdTe-GSH quantum dots with improved biocompatibility.PloS one · 2012Article
- Enhanced glutathione content allows the in vivo synthesis of fluorescent CdTe nanoparticles by Escherichia coli.PloS one · 2012Article
- In vivo imaging of immune cell trafficking in cancer.European journal of nuclear medicine and molecular imaging · 2011Review
- Designing multifunctional quantum dots for bioimaging, detection, and drug delivery.Chemical Society reviews · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the development of nanotechnology, nanoscale products that are smaller than several hundred nanometers have been applied to all areas of science and technology. Nanoscale products, including carbon nanotubes, fullerene derivatives, and nanocrystal quantum dots (QDs), are wide spread as novel tools in various fields, not only in materials engineering, electronics, plastics, and the automobile and aerospace industries, but also in molecular biology and medicine. At present, QDs have been widely used in biological and medical studies because of their superior photoemission and photostability. Although the physical and chemical properties of QDs have been circumstantially investigated, little is known about any harmful effects of QDs on human health. Here we report on the toxicity and biological behavior of QDs in vitro and in vivo. The toxicity of the core constituent chemicals such as cadmium and selenium has been identified. Recently, the surface molecules surrounding QDs have been intensively investigated. Accumulating evidence that toxic surface-covering molecules showed their cytotoxicity and biomolecules conjugated with QDs maintained their biological effects indicates that at least the biological properties of QDs are attributable to the QD-capping material rather than to the core metalloid complex itself.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.