Evidence map›Paper›PMID 17846140›Full record

ArticleAntimicrobial agents and chemotherapy2007

Antibiotic resistance and single-nucleotide polymorphism cluster grouping type in a multinational sample of resistant Mycobacterium tuberculosis isolates.

M Brimacombe, M Hazbon, A S Motiwala, D Alland

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Genotype of a historic strain of Mycobacterium tuberculosis.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M BrimacombeDepartment of Preventive Medicine and Community Health, New Jersey Medical School-UMDNJ, 185 S. Orange Ave., MSB F-647, Newark, NJ 07083, USA. brimacmb@umdnj.edu
M Hazbon
A S Motiwala
D Alland

Funding

POPULATION BASED INVESTIGATIONS OF TUBERCULOSISR01AI046669 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI ALLAND, DAVID · 2000 to 2004
$2.5M
TUBERCULOSIS GENOTYPING AND EVOLUTIONARY CONSORTIUMR01AI049352 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI ALLAND, DAVID · 2002 to 2005
$2.0M
NIAID NIH HHS AI-46669NIAID NIH HHS AI-49352NIAID NIH HHS R01 AI046669NIAID NIH HHS R01 AI049352
6 · The paper itself

Abstract

A single-nucleotide polymorphism-based cluster grouping (SCG) classification system for Mycobacterium tuberculosis was used to examine antibiotic resistance type and resistance mutations in relationship to specific evolutionary lineages. Drug resistance and resistance mutations were seen across all SCGs. SCG-2 had higher proportions of katG codon 315 mutations and resistance to four drugs.

Indexed as

Polymorphism, Single NucleotideBacterial ProteinsBacterial Typing TechniquesCatalaseDrug Resistance, MicrobialMicrobial Sensitivity TestsMycobacterium tuberculosisBacterial ProteinsCatalasekatG protein, Mycobacterium tuberculosis

Identifiers

PMID17846140
PMCPMC2151444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.