Evidence map›Paper›PMID 17845100›Full record

SynthesisHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2007

Lifestyle interventions in the treatment of childhood overweight: a meta-analytic review of randomized controlled trials.

Denise E Wilfley, Tiffany L Tibbs, Dorothy J Van Buren, Kelle P Reach, Mark S Walker, Leonard H Epstein

3 registry-linked trialsOpen access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT01410604. Cited by 138 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 9 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01410604 phase4completed

Inflammatory Mediators in Obese Adolescents With Insulin Resistance Following Metformin Treatment: Controlled Randomized Clinical Trial

Ran2007Enrolled31Registered outcomes8Posted comparisons0ConditionsObesityArmsMetformin, Placebo
PMID 18492523PMID 18597869PMID 16595599PMID 11602624PMID 17015542PMID 10699131PMID 10797032PMID 11134477PMID 11172066PMID 11295710PMID 11344187PMID 11681807other papers from this trial
Open the trial in the graph
NCT05124847 nacompletednot on this mapstarted 2021, after this paper: background citation

Time Restricted Eating as a Treatment for Pediatric Obesity

TypeinterventionalSponsorFundación Pública Andaluza para la Investigación de Málaga en Biomedicina y SaludRan2021 to 2023Enrolled30ConditionsInfant Obesity, Hepatic Steatosis, Metabolic Syndrome, Insulin ResistanceArmsStandard Care, Time restricted eating
NCT06239662 nacompletednot on this mapstarted 2016, after this paper: background citation

Therapeutic Education Groups for Childhood Obesity: a Randomized Controlled Trial

TypeinterventionalSponsorAzienda USL Reggio Emilia - IRCCSRan2016 to 2023Enrolled318ConditionsChildhood ObesityArmsTherapeutic Group, Usual care
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 9 syntheses or guidelines pooled it, 367 citations in OpenAlex.

  1. Clinically effective child change in family-based behavioral treatment for pediatric obesity: An individual participant mega-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  7. Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline.The Journal of clinical endocrinology and metabolism · 2017 · on this map
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Denise E WilfleyDepartment of Psychiatry, Washington University School of Medicine, MO 63110, USA. wilfleyd@psychiatry.wustl.edu
Tiffany L Tibbs
Dorothy J Van Buren
Kelle P Reach
Mark S Walker
Leonard H Epstein
Washington University in St. Louis · USUniversity at Buffalo, State University of New York · US

Funding

WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
TRANSGENICS COREP60DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI SCHAFFER, JEAN E. · 1986 to 2012
$25.2M
CHILDHOOD OBESITY TREATMENT: A MAINTENANCE APPROACHR01HD036904 · NICHD · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 1999 to 2010
$6.8M
EFFECTS OF CHANGING SEDENTARY BEHAVIOR IN OBESE CHILDRENR01HD039778 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2001 to 2008
$2.3M
Habituation to Food in ChildrenR01HD044725 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2003 to 2009
$2.1M
A BEHAVIORAL ECONOMIC APPROACH TO CHILDHOOD OBESITYR01HD039792 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2001 to 2005
$1.7M
Modifying the home T.V. watching environmentR01DK063442 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EPSTEIN, LEONARD H · 2002 to 2005
$1.5M
Clinical Research in Eating Disorders and ObesityK24MH070446 · NIMH · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 2004 to 2013
$1.4M
NICHD NIH HHS HD036904NICHD NIH HHS HD39778NICHD NIH HHS HD39792NICHD NIH HHS HD44725NICHD NIH HHS R01 HD036904NICHD NIH HHS R01 HD039778NICHD NIH HHS R01 HD039792NICHD NIH HHS R01 HD044725NIDDK NIH HHS DK020579NIDDK NIH HHS DK63442NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P60 DK020579NIDDK NIH HHS R01 DK063442NIMH NIH HHS K24 MH070446NIMH NIH HHS MH070446
6 · The paper itself

Abstract

contextEvaluating the efficacy of pediatric weight loss treatments is critical.

objectiveThis is the first meta-analysis of the efficacy of RCTs comparing pediatric lifestyle interventions to no-treatment or information/education-only controls. DATA SOURCES: Medline, PsycINFO, and Cochrane Controlled Trials Register. STUDY SELECTION: Fourteen RCTs targetting change in weight status were eligible, yielding 19 effect sizes. DATA EXTRACTION: Standardized coding was used to extract information on design, participant characteristics, interventions, and results. DATA SYNTHESIS: For trials with no-treatment controls, the mean effect size was 0.75 (k = 9, 95% confidence interval [CI] = 0.52-0.98) at end of treatment and 0.60 (k = 4, CI = 0.27-0.94) at follow-up. For trials with information/education-only controls, the mean ES was 0.48 (k = 4, CI = 0.13-0.82) at end of treatment and 0.91 (k = 2, CI = 0.32-1.50) at follow-up. No moderator effects were identified.

conclusionsLifestyle interventions for pediatric overweight are efficacious in the short term with some evidence for extended persistence. Future research is required to identify moderators and mediators and to determine the optimal length and intensity of treatment required to produce enduring changes in weight status.

Indexed as

Risk Reduction BehaviorAdolescentChildChild, PreschoolFemaleHumansMaleOverweightRandomized Controlled Trials as TopicTreatment OutcomeUnited States

Identifiers

PMID17845100
PMCPMC2040042
OpenAlexW2088619891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.