Evidence map›Paper›PMID 17828606›Full record

ArticleParasitology research2007

Liver stage antigen 3 isolated from a cDNA library of Plasmodium falciparum erythrocytic stages.

Eva M Moyano, Luis Miguel González, Susana Arahuetes, Agustín Benito

Abstract read
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In one paragraph

Article in Parasitology research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eva M MoyanoCentro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Sinesio Delgado, 6, Pabellózn 13, 28020, Madrid, Spain.
Luis Miguel González
Susana Arahuetes
Agustín Benito

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An expression library of P. falciparum erythrocyte stages (clon Dd2) was constructed and immunoscreened with a sera pool from malaria patients. Isolated clones were analysed, and the liver stage antigen 3 (LSA-3) antigen was identified. The partial nucleotide sequence of LSA-3 has 1,623 bp. The open reading frame coded for the putative protein with 541 amino acid residues. We have demonstrated by reverse transcriptase polymerase chain reaction the transcription of the LSA-3 gene in ring form, trophozoite, and schizont, stages of asexual erythrocyte cycle.

Indexed as

Gene LibraryAnimalsAntigens, ProtozoanGene Expression RegulationLife Cycle StagesPlasmodium falciparumReverse Transcriptase Polymerase Chain ReactionAntigens, Protozoanliver stage-specific antigen, Plasmodium

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.