ReviewJournal of clinical immunology2008
Biology of dendritic cells in aging.
Review in Journal of clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- Immunosenescence: A systems-level overview of immune cell biology and strategies for improving vaccine responses.Experimental gerontology · 2019Pooled it
- Cardiovascular exercise intervention improves the primary antibody response to keyhole limpet hemocyanin (KLH) in previously sedentary older adults.Brain, behavior, and immunity · 2008Trial
- Regulatory RNAs in immunosenescence.Immunity, inflammation and disease · 2024Review
- The impact of aging-induced gut microbiome dysbiosis on dendritic cells and lung diseases.Gut microbes · 2023Review
- The aging of the immune system and its implications for transplantation.GeroScience · 2023Review
- Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity.Immune network · 2019Review
- Blood immune cell biomarkers in lung cancer.Clinical and experimental immunology · 2019Article
- Transplantation of Marginal Organs: Immunological Aspects and Therapeutic Perspectives in Kidney Transplantation.Frontiers in immunology · 2019Review
- Effects of Acute and Chronic Exercise on Immunological Parameters in the Elderly Aged: Can Physical Activity Counteract the Effects of Aging?Frontiers in immunology · 2018Review
- Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.PloS one · 2018Article
- Considerations for successful cancer immunotherapy in aged hosts.Clinical and experimental immunology · 2017Review
- Article
- Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Ocular surface disease and dacryoadenitis in aging C57BL/6 mice.The American journal of pathology · 2014Article
- Preoperative cerebrospinal fluid cytokine levels and the risk of postoperative delirium in elderly hip fracture patients.Journal of neuroinflammation · 2013Article
- Immunosenescence and organ transplantation.Transplantation reviews (Orlando, Fla.) · 2013Review
- Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Vaccination in the elderly.Microbial biotechnology · 2012Review
- Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.The Journal of clinical investigation · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Dendritic cells are central to the generation of both immunity and tolerance. This review focuses on the alterations in the functions of dendritic cells in aged and its consequences on both tolerance and immunity. We have discussed certain mechanisms responsible for the defective dendritic cell function associated with aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.