ReviewJournal of clinical oncology : official journal of the American Society of Clinical Oncology2007
Antiangiogenics: the potential role of integrating this novel treatment modality with chemoradiation for solid cancers.
Review in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00842686 (Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer), which is not on this map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study
Who cites it
41 citing papers in PubMed.
- Salvage therapy with single agent bevacizumab for recurrent glioblastoma.Journal of neuro-oncology · 2010Trial
- New approaches to overcome radioresistance in glioblastoma: mechanisms, targets and role of innovative therapies, new particles and non-photon radiotherapy in 2024. A systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Review
- Review
- The Combination of Immune Checkpoint Blockade with Tumor Vessel Normalization as a Promising Therapeutic Strategy for Breast Cancer: An Overview of Preclinical and Clinical Studies.International journal of molecular sciences · 2023Review
- Manipulation of immune‒vascular crosstalk: new strategies towards cancer treatment.Acta pharmaceutica Sinica. B · 2020Review
- Risk factors for severe gastrointestinal toxicity in patients receiving palliative radiotherapy for metastatic bone tumors: association with the use of molecular-targeted agents.Journal of radiation research · 2020Article
- Expression of Programmed Cell Death Protein 1 by Tumor-Infiltrating Lymphocytes and Tumor Cells is Associated with Advanced Tumor Stage in Patients with Esophageal Adenocarcinoma.Annals of surgical oncology · 2017Article
- Ischemic stroke and intracranial hemorrhage in patients with recurrent glioblastoma multiforme, treated with bevacizumab.Journal of neuro-oncology · 2017Article
- Blockade of vascular endothelial growth factor receptors by tivozanib has potential anti-tumour effects on human glioblastoma cells.Scientific reports · 2017Article
- Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights.Scientific reports · 2016Article
- Current status and future directions of anti-angiogenic therapy for gliomas.Neuro-oncology · 2016Review
- Nanomedicines for Endothelial Disorders.Nano today · 2015Article
- Cancer therapeutic potential of combinatorial immuno- and vasomodulatory interventions.Journal of the Royal Society, Interface · 2015Article
- Antiangiogenic therapy for glioblastoma: current status and future prospects.Clinical cancer research : an official journal of the American Association for Cancer Research · 2014Review
- Induced interleukin-33 expression enhances the tumorigenic activity of rat glioma cells.Neuro-oncology · 2014Article
- Clinical response to sunitinib as a multitargeted tyrosine-kinase inhibitor (TKI) in solid cancers: a review of clinical trials.OncoTargets and therapy · 2014Review
- Phase I trial of preoperative chemoradiation plus sorafenib for high-risk extremity soft tissue sarcomas with dynamic contrast-enhanced MRI correlates.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013Article
- Piperine, a dietary phytochemical, inhibits angiogenesis.The Journal of nutritional biochemistry · 2013Article
- Human endothelial progenitor cells.Cold Spring Harbor perspectives in medicine · 2012Review
- Flow cytometric identification and functional characterization of immature and mature circulating endothelial cells.Arteriosclerosis, thrombosis, and vascular biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Although still in very early stages of clinical development, the combination of antiangiogenics with contemporary chemoradiotherapy regimens has emerged as a feasible and promising approach to many cancers. We review the rationale and the current understanding of antiangiogenics and their therapeutic potential in combination with chemoradiotherapy. Finally, we offer a perspective on future research directions aimed at making this complex therapeutic approach successful in the clinic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.