Evidence map›Paper›PMID 17827314›Full record

ArticleApplied and environmental microbiology2007

Retrospective characterization of a vaccine-derived poliovirus type 1 isolate from sewage in Greece.

Evaggelos Dedepsidis, Zaharoula Kyriakopoulou, Vaia Pliaka, Christine Kottaridi, Eugenia Bolanaki, Stamatina Levidiotou-Stefanou, Dimitri Komiotis, Panayotis Markoulatos

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. The final stages of the global eradication of poliomyelitis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evaggelos DedepsidisDepartment of Biochemistry & Biotechnology, University of Thessaly, 26 Ploutonos & Aiolou Str., Larissa 41221, Greece.
Zaharoula Kyriakopoulou
Vaia Pliaka
Christine Kottaridi
Eugenia Bolanaki
Stamatina Levidiotou-Stefanou
Dimitri Komiotis
Panayotis Markoulatos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrospective molecular and phenotypic characterization of a vaccine-derived poliovirus (VDPV) type 1 isolate (7/b/97) isolated from sewage in Athens, Greece, in 1997 is reported. VP1 sequencing of this isolate revealed 1.87% divergence from the VP1 region of reference strain Sabin 1, while further genomic characterization of isolate 7/b/97 revealed a recombination event in the nonstructural part of the genome between a vaccine strain and a nonvaccine strain probably belonging to Enterovirus species C. Amino acid substitutions commonly found in previous studies were identified in the capsid coding region of the isolate, while most of the attenuation and temperature sensitivity determinants were reverted. The ultimate source of isolate 7/b/97 is unknown. The recovery of such a highly divergent derivative of a vaccine strain emphasizes the need for urgent implementation of environmental surveillance as a supportive procedure in the polio surveillance system even in countries with high rates of OPV coverage in order to prevent cases or even outbreaks of poliomyelitis that otherwise would be inevitable.

Indexed as

Poliovirus Vaccine, OralCapsid ProteinsGreeceHumansPoliomyelitisPoliovirusRecombination, GeneticRetrospective StudiesSequence Analysis, DNASewageCapsid ProteinsPoliovirus Vaccine, OralSewageVP1 protein, Poliovirus

Identifiers

PMID17827314
PMCPMC2074943

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.