Evidence map›Paper›PMID 17827287›Full record

ArticleJournal of bacteriology2007

Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon.

Luis Caetano M Antunes, Amy L Schaefer, Rosana B R Ferreira, Nan Qin, Ann M Stevens, Edward G Ruby, E Peter Greenberg

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
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  7. Surfactin Facilitates Horizontal Gene Transfer inFrontiers in microbiology · 2021
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  14. Review
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  18. Why Quorum Sensing Controls Private Goods.Frontiers in microbiology · 2017
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luis Caetano M AntunesDepartment of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.
Amy L Schaefer
Rosana B R Ferreira
Nan Qin
Ann M Stevens
Edward G Ruby
E Peter Greenberg
University of Washington · USVirginia Tech · USUniversity of Wisconsin–Madison · US

Funding

Cell-Cell Communicaton in Bacterial Quorum SensingR01GM066786 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI LEVCHENKO, ANDRE · 2003 to 2008
$1.6M
NIGMS NIH HHS GM066786NIGMS NIH HHS R01 GM066786
6 · The paper itself

Abstract

The Vibrio fischeri quorum-sensing signal N-3-oxohexanoyl-l-homoserine lactone (3OC6-HSL) activates expression of the seven-gene luminescence operon. We used microarrays to unveil 18 additional 3OC6-HSL-controlled genes, 3 of which had been identified by other means previously. We show most of these genes are regulated by the 3OC6-HSL-responsive transcriptional regulator LuxR directly. This demonstrates that V. fischeri quorum sensing regulates a substantial number of genes other than those involved in light production.

Indexed as

Gene Expression ProfilingGene Expression Regulation, Bacterial4-ButyrolactoneAliivibrio fischeriBacterial ProteinsLuminescenceOligonucleotide Array Sequence AnalysisOperonPromoter Regions, GeneticProtein BindingQuorum SensingRegulonRepressor ProteinsTrans-ActivatorsTranscription Factors4-ButyrolactoneBacterial ProteinsLuxI protein, BacteriaLuxR autoinducer binding proteinsN-(3-oxohexanoyl)-3-aminodihydro-2(3H)-furanoneRepressor ProteinsTrans-ActivatorsTranscription Factors

Identifiers

PMID17827287
PMCPMC2168698
OpenAlexW2139747480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.