ArticleDevelopmental biology2007
Drosophila Myosin II, Zipper, is essential for ommatidial rotation.
Article in Developmental biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila.Cell reports · 2022Article
- Wnt-frizzled planar cell polarity signaling in the regulation of cell motility.Current topics in developmental biology · 2022Review
- Tissue fluidity mediated by adherens junction dynamics promotes planar cell polarity-driven ommatidial rotation.Nature communications · 2021Article
- Notch signaling coordinates ommatidial rotation in the Drosophila eye via transcriptional regulation of the EGF-Receptor ligand Argos.Scientific reports · 2019Article
- Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix.Open biology · 2019Article
- Counter-rotational cell flows drive morphological and cell fate asymmetries in mammalian hair follicles.Nature cell biology · 2018Article
- Dynamics of cell polarity in tissue morphogenesis: a comparative view from Drosophila and Ciona.F1000Research · 2016Review
- Tissue patterning and cellular mechanics.The Journal of cell biology · 2015Review
- Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer.Cellular and molecular life sciences : CMLS · 2014Review
- Nemo regulates cell dynamics and represses the expression of miple, a midkine/pleiotrophin cytokine, during ommatidial rotation.Developmental biology · 2013Article
- Article
- Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin.Nature structural & molecular biology · 2011Article
- Planar cell polarity signaling in the Drosophila eye.Current topics in developmental biology · 2010Review
- The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye.Development (Cambridge, England) · 2009Article
- Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila.Developmental biology · 2009Article
- Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.Development (Cambridge, England) · 2009Article
- Nemo is required in a subset of photoreceptors to regulate the speed of ommatidial rotation.Developmental biology · 2008Article
- Planar cell polarity signaling: coordination of cellular orientation across tissues.Wiley interdisciplinary reviews. Developmental biologyReview
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Authors and funding
2 authors.
Funding
Abstract
The adult Drosophila retina is a highly polarized epithelium derived from a precursor tissue that is initially symmetric across its dorsoventral axis. Specialized 90 degrees rotational movements of subsets of cells, the ommatidial precursors, establish mirror symmetry in the retinal epithelium. Myosin II, or Zipper (Zip), a motor protein, regulates the rate at which ommatidia rotate: in zip mutants, the rate of rotation is significantly slowed. Zip is concentrated in the cells that we show to be at the likely interface between rotating and non-rotating cells: the boundary between differentiated and undifferentiated cells. Zip is also robust in newly added ommatidial cells, consistent with our model that the machinery that drives rotation should shift to newly recruited cells as they are added to the growing ommatidium. Finally, cell death genes and canonical Wnt signaling pathway members genetically modify the zip phenotype.
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