ReviewMolecular immunology2008
Quantitative challenges in understanding ligand discrimination by alphabeta T cells.
Review in Molecular immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed.
- A comparative mathematical modeling study of phenotypic approaches to T cell activation.Scientific reports · 2025Article
- Ligand discrimination in immune cells: Signal processing insights into immune dysfunction in ER+ breast cancer.PLoS computational biology · 2025Article
- Dynamical model and geometric insights in the discontinuity theory of immunity.bioRxiv : the preprint server for biology · 2025Article
- Positron Emission Tomography Imaging of the Adaptive Immune System in Cardiovascular Diseases.Chemical & biomedical imaging · 2025Review
- TCR-T cell therapy for solid tumors: challenges and emerging solutions.Frontiers in pharmacology · 2025Review
- Article
- Limits on the accuracy of contact inhibition of locomotion.Physical review. E · 2024Article
- Modulation of antigen discrimination by duration of immune contacts in a kinetic proofreading model of T cell activation with extreme statistics.PLoS computational biology · 2023Article
- Proofreading does not result in more reliable ligand discrimination in receptor signaling due to its inherent stochasticity.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- T cell microvilli simulations show operation near packing limit and impact on antigen recognition.Biophysical journal · 2022Article
- Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination.Nature immunology · 2022Article
- Review
- Relaxation Times of Ligand-Receptor Complex Formation Control T Cell Activation.Biophysical journal · 2020Article
- Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.Nature immunology · 2019Article
- A cell topography-based mechanism for ligand discrimination by the T cell receptor.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Towards multiscale modeling of the CD8Wiley interdisciplinary reviews. Systems biology and medicine · 2019Review
- Is TCR/pMHC Affinity a Good Estimate of the T-cell Response? An Answer Based on Predictions From 12 Phenotypic Models.Frontiers in immunology · 2019Article
- Article
- Multiple steady states and the form of response functions to antigen in a model for the initiation of T-cell activation.Royal Society open science · 2017Article
- Untangling the Hairball: Fitness-Based Asymptotic Reduction of Biological Networks.Biophysical journal · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.