Assessment of antibody protection against malaria sporozoites must be done by mosquito injection of sporozoites.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. Controlled Human Malaria Infection Studies in Africa-Past, Present, and Future.Current topics in microbiology and immunology · 2024
   Review
2. Antibodies against Plasmodium falciparum malaria at the molecular level.Nature reviews. Immunology · 2019
   Review
3. Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells.Frontiers in immunology · 2019
   Article
4. Infection via mosquito bite alters Zika virus tissue tropism and replication kinetics in rhesus macaques.Nature communications · 2017
   Article
5. Humoral protection against mosquito bite-transmittedNPJ vaccines · 2017
   Article
6. An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: bridging traditional mouse malaria models and human trials.Future microbiology · 2016
   Review
7. Active migration and passive transport of malaria parasites.Trends in parasitology · 2015
   Review
8. Plasmodium cellular effector mechanisms and the hepatic microenvironment.Frontiers in microbiology · 2015
   Review
9. Measurement of Antibody-Mediated Reduction of Plasmodium yoelii Liver Burden by Bioluminescent Imaging.Methods in molecular biology (Clifton, N.J.) · 2015
   Article
10. Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies.Malaria journal · 2014
    Article
11. Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum.Malaria journal · 2014
    Article
12. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum.Infection and immunity · 2014
    Article
13. Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities.PloS one · 2014
    Article
14. Is arthropod saliva the achilles' heel of vector-borne diseases?Frontiers in immunology · 2013
    Review
15. Self-adjuvanting bacterial vectors expressing pre-erythrocytic antigens induce sterile protection against malaria.Frontiers in immunology · 2013
    Article
16. Protective CD8+ T lymphocytes in primates immunized with malaria sporozoites.PloS one · 2012
    Article
17. Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy.Malaria journal · 2010
    Article
18. Immunity to malaria: more questions than answers.Nature immunology · 2008
    Review

Corrections and comments

• Comment on
  Genetically attenuated Plasmodium berghei liver stages persist and elicit sterile protection primarily via CD8 T cells.2007

Authors and funding

7 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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