ReviewPostgraduate medical journal2007
The role of genetics in stroke.
Review in Postgraduate medical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Genetic susceptibility to cerebrovascular disease: A systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2018Pooled it
- Public awareness and knowledge of stroke risk factors and symptoms in Saudi Arabia: A cross-sectional study.ARYA atherosclerosis · 2025Article
- Cigarette smoking as a risk factor for ischaemic stroke in young South Asian male migrants to Qatar: The BRAINS study.Qatar medical journal · 2023Article
- Blood-Brain Barrier Mechanisms in Stroke and Trauma.Handbook of experimental pharmacology · 2022Review
- Association of methylenetetrahydrofolate reductase (MTHFR) rs1801133 (677C>T) gene polymorphism with ischemic stroke risk in different populations: An updated meta-analysis.Frontiers in genetics · 2022Review
- Protein C Promotor Haplotypes Associated with Large-Artery Atherosclerosis Stroke in Iranian Population.Journal of molecular neuroscience : MN · 2021Article
- MTHFR A1298C gene polymorphism on stroke risk: an updated meta-analysis.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021Article
- Noonan Syndrome with Multiple Lentigines andMolecular syndromology · 2021Article
- Heritability for stroke: Essential for taking family history.Caspian journal of internal medicine · 2020Review
- Conflicting Roles of 20-HETE in Hypertension and Stroke.International journal of molecular sciences · 2019Review
- Nucleic Acid Therapies for Ischemic Stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019Review
- Morphogenetic Variability and Hypertension in Ischemic Stroke Patients-Preliminary Study.Journal of clinical medicine · 2018Article
- Association study of C-reactive protein associated gene HNF1A with ischemic stroke in Chinese population.BMC medical genetics · 2016Article
- Genetic susceptibility to cerebrovascular disease.Current opinion in lipidology · 2016Review
- Inherited neurovascular diseases affecting cerebral blood vessels and smooth muscle.Metabolic brain disease · 2015Review
- SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis.BioMed research international · 2015Article
- Homozygous mutation in SAMHD1 gene causes cerebral vasculopathy and early onset stroke.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Stroke in young in India.Stroke research and treatment · 2010Article
- Mutation patterns in human alpha-galactosidase A.Molecular diversity · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stroke is a leading cause of death and disability in developed countries. While both modifiable and non-modifiable risk factors are acknowledged, studies have shown that these may account for just 50% of stroke risk and that other factors, including genetic ones, may be important. Over recent years family history, twin and candidate gene studies have supported this and various mendelian stroke syndromes have now been identified in humans. This article provides an up-to-date summary of the common single gene disorders associated with stroke as a principle manifestation, including their genetic basis, pathogenesis, presentation and suggested management. Often these disorders present with stroke at a young age; this article provides a practical approach to the management and investigation of a young stroke patient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.