Evidence map›Paper›PMID 17805417›Full record

ArticleEnvironmental health perspectives2007

Traffic-related atmospheric pollutants levels during pregnancy and offspring's term birth weight: a study relying on a land-use regression exposure model.

Rémy Slama, Verena Morgenstern, Josef Cyrys, Anne Zutavern, Olf Herbarth, Heinz-Erich Wichmann, Joachim Heinrich, LISA Study Group

3 registry-linked trialsAbstract read
In one paragraph

Article in Environmental health perspectives, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 74 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02786420 completednot on this mapstarted 2015, after this paper: background citation

Imaging Innovations for Placental Assessment in Response to Environmental Pollution

TypeobservationalSponsorUniversity of California, Los AngelesRan2015 to 2020Enrolled199ConditionsPlacental Disease
NCT02852499 unknown statusnot on this mapstarted 2014, after this paper: background citation

SEPAGES : Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health

TypeobservationalSponsorUniversity Hospital, GrenobleRan2014 to 2021Enrolled1,010ConditionsHealthy VolunteerArmsUrine sampling, Carry a GPS and BET, Carry pollution sensor, Sampling at the maternity, Self-questionnaires
NCT05316025 unknown statusnot on this mapstarted 2022, after this paper: background citation

Grenoble Cardiovascular Digital Health Data Observatory

Typeobservational_patient_registrySponsorUniversity Hospital, GrenobleRan2022 to 2025Enrolled5,000ConditionsCardiovascular Diseases, Digital, Health Data, Observatory
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Adverse Birth Outcomes Related to NOInternational journal of environmental research and public health · 2020
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Pathogenesis of PMEpigenomes · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Life Course of Asthma.Advances in experimental medicine and biology · 2023
    Article
  10. In-utero personal exposure to PMEnvironmental advances · 2022
    Article
  11. Air pollution exposure impairs lung function in infants.Acta paediatrica (Oslo, Norway : 1992) · 2022
    Article
  12. Exposure to Traffic Density during Pregnancy and Birth Weight in a National Cohort, 2000-2017.International journal of environmental research and public health · 2022
    Article
  13. Exposure to Ambient Air Pollutant PMBioMed research international · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Association between the pregnancy exposome and fetal growth.International journal of epidemiology · 2020
    Article
  19. Maternal exposure to air pollutants and birth weight in Tehran, Iran.Journal of environmental health science & engineering · 2019
    Article
  20. Assessment of Traffic-Related Air Pollution: Case Study of Pregnant Women in South Texas.International journal of environmental research and public health · 2019
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rémy SlamaGSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany. slama@vjf.inserm.fr
Verena Morgenstern
Josef Cyrys
Anne Zutavern
Olf Herbarth
Heinz-Erich Wichmann
Joachim Heinrich
LISA Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome studies have suggested that particulate matter (PM) levels during pregnancy may be associated with birth weight. Road traffic is a major source of fine PM (PM with aero-dynamic diameter < 2.5 microm; PM(2.5)).

objectiveWe determined to characterize the influence of maternal exposure to atmospheric pollutants due to road traffic and urban activities on offspring term birth weight.

methodsWomen from a birth cohort [the LISA (Influences of Lifestyle Related Factors on the Human Immune System and Development of Allergies in Children) cohort] who delivered a non-premature baby with a birth weight > 2,500 g in Munich metropolitan area were included. We assessed PM(2.5), PM(2.5) absorbance (which depends on the blackness of PM(2.5), a marker of traffic-related air pollution), and nitrogen dioxide levels using a land-use regression model, taking into account the type and length of roads, population density, land coverage around the home address, and temporal variations in pollution during pregnancy. Using Poisson regression, we estimated prevalence ratios (PR) of birth weight < 3,000 g, adjusted for gestational duration, sex, maternal smoking, height, weight, and education.

resultsExposure was defined for 1,016 births. Taking the lowest quartile of exposure during pregnancy as a reference, the PR of birth weight < 3,000 g associated with the highest quartile was 1.7 for PM(2.5) [95% confidence interval (CI), 1.2-2.7], 1.8 for PM(2.5) absorbance (95% CI, 1.1-2.7), and 1.2 for NO(2) (95% CI, 0.7-1.7). The PR associated with an increase of 1 microg/m(3) in PM(2.5) levels was 1.13 (95% CI, 1.00-1.29).

conclusionIncreases in PM(2.5) levels and PM(2.5) absorbance were associated with decreases in term birth weight. Traffic-related air pollutants may have adverse effects on birth weight.

Indexed as

Air PollutantsBirth WeightFemaleGeographic Information SystemsGermanyHumansInfant, NewbornMaleMaternal ExposureModels, TheoreticalNitrogen DioxideParticulate MatterPregnancyRegression AnalysisVehicle EmissionsAir PollutantsNitrogen DioxideParticulate MatterVehicle Emissionsatmospheric pollutionbirth weightdiesel sootenvironmentgeographic information systemintrauterine growth restrictionparticulate matterpregnancyreproductionroad trafficsensitivity analysis

Identifiers

PMID17805417
PMCPMC1964922

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.