Evidence map›Paper›PMID 17803817›Full record

ArticleGenome biology2007

Cross-species cluster co-conservation: a new method for generating protein interaction networks.

Anis Karimpour-Fard, Corrella S Detweiler, Kimberly D Erickson, Lawrence Hunter, Ryan T Gill

Abstract read
In one paragraph

Article in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. SalmoNet, an integrated network of tenNPJ systems biology and applications · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anis Karimpour-FardCenter for Computational Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA.
Corrella S Detweiler
Kimberly D Erickson
Lawrence Hunter
Ryan T Gill

Funding

Technology Development for a MolBio Knowledge-BaseR01LM008111 · NLM · UNIVERSITY OF COLORADO DENVER · PI HUNTER, LAWRENCE E · 2004 to 2021
$9.7M
Persistent Systemic Infection of Mice by Salmonella EntericaR01AI072492 · NIAID · UNIVERSITY OF COLORADO · PI DETWEILER, CORRELLA S · 2007 to 2011
$1.8M
BioMolecular Networks in Antibiotic Resistance EvolutionK25AI064338 · NIAID · UNIVERSITY OF COLORADO AT BOULDER · PI GILL, RYAN T · 2005 to 2008
$564k
The Salmonella RcsC Phosphorelay System and VirulenceR56AI063116 · NIAID · UNIVERSITY OF COLORADO AT BOULDER · PI DETWEILER, CORRELLA · 2005 to 2005
$320k
NIAID NIH HHS K25 AI064338NIAID NIH HHS R01 AI072492NIAID NIH HHS R01-AI-072492ANIAID NIH HHS R56 AI063116NLM NIH HHS R01 LM008111NLM NIH HHS R01-LM-008111
6 · The paper itself

Abstract

Co-conservation (phylogenetic profiles) is a well-established method for predicting functional relationships between proteins. Several publicly available databases use this method and additional clustering strategies to develop networks of protein interactions (cluster co-conservation (CCC)). CCC has previously been limited to interactions within a single target species. We have extended CCC to develop protein interaction networks based on co-conservation between protein pairs across multiple species, cross-species cluster co-conservation.

Indexed as

AlgorithmsBiofilmsCluster AnalysisComputational BiologyDatabases, ProteinEscherichia coliGammaproteobacteriaLikelihood FunctionsModels, BiologicalModels, GeneticModels, StatisticalPhylogenyProtein Interaction MappingShigella flexneriSpecies Specificity

Identifiers

PMID17803817
PMCPMC2375023

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.