ArticleClinical cardiology2007
Glomerular filtration rate and coronary artery disease burden in patients with acute coronary syndrome.
Article in Clinical cardiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Coronary Artery Disease and Chronic Kidney Disease: A Tale of Two Organs.Arquivos brasileiros de cardiologia · 2026Article
- Kidney Function Does Not Modify the Favorable Quality of Life Changes Associated With Revascularization for Coronary Artery Disease: Cohort Study.Journal of the American Heart Association · 2016Article
- Article
- Systemic correlates of angiographic coronary artery disease.PloS one · 2009Article
- Myocardial perfusion scintigraphy in myocardial infarction - impact of ST-segment elevation and of Diabetes mellitus.Porto biomedical journalArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMild renal dysfunction may be associated with increased cardiovascular morbidity and mortality.
methodsThe relation between estimated glomerular filtration rate (eGFR), as calculated from plasma creatinine at admission, and coronary artery disease burden (CADB), was studied in a cohort of 110 patients with acute coronary syndrome and coronary atherosclerosis.
resultsA relatively weak but significant negative correlation was found between eGFR and CADB as measured by angiography (coefficient correlation of - 0.26, probability value of 0.006); a similar association was seen in multiple regression analysis, taking CADB as dependent variable, and eGFR, age, plasma calcium and plasma phosphorus as independent variables. After dividing the 110 patients into eGFR tertiles (with mean values of 102.9 +/- 22.8, n = 37, 75.7 + or - 5.6, n = 36, and 53.1 +/- 13.4, n = 37, all in mL/min per 1.73 m(2)), mean CADB values of the lower and higher eGFR tertiles were found to be significantly different (270.6 +/- 176.4 and 192.9 +/- 78.5, respectively). Similar mean values for CADB and for eGFR were noted when patients with elevated ST segment/new left bundle branch block and patients with nonelevated ST segment acute coronary syndrome were compared.
conclusionsWe conclude that renal function of patients with acute coronary syndromes and coronary atherosclerosis, as estimated at admission, is negatively correlated with coronary artery disease burden. It is unknown whether renal dysfunction acts as a cause for accelerated coronary artery disease or if it merely acts as a surrogate marker for the overall systemic vascular system status.
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