Evidence map›Paper›PMID 17786587›Full record

ReviewJournal of structural and functional genomics2007

Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics.

George N Phillips, Brian G Fox, John L Markley, Brian F Volkman, Euiyoung Bae, Eduard Bitto, Craig A Bingman, Ronnie O Frederick, Jason G McCoy, Betsy L Lytle and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of structural and functional genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. The Protein Model Portal--a comprehensive resource for protein structure and model information.Database : the journal of biological databases and curation · 2013
    Article
  3. Article
  4. Article
  5. Article
  6. Rapid, robotic, small-scale protein production for NMR screening and structure determination.Protein science : a publication of the Protein Society · 2010
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

George N PhillipsCenter for Eukaryotic Structural Genomics, Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. Phillips@biochem.wisc.edu
Brian G Fox
John L Markley
Brian F Volkman
Euiyoung Bae
Eduard Bitto
Craig A Bingman
Ronnie O Frederick
Jason G McCoy
Betsy L Lytle
Brad S Pierce
Jikui Song
Simon N Twigger

Funding

Center for Eukaryotic Structural GenomicsP50GM064598 · NIGMS · UNIVERSITY OF WISCONSIN MADISON · PI MARKLEY, JOHN L · 2001 to 2004
$23.7M
Research Training for Computation and Informatics in Biology and MedicineT15LM007359 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI Mark W. Craven, Colin Noel Dewey · 2002 to 2026
$22.6M
Specialized Center for Eukaryotic Structural GenomicsU54GM074901 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2005 to 2009
$18.9M
Institutional Training in the Genomic SciencesT32HG002760 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI Qiongshi Lu · 2003 to 2026
$17.7M
ROLE OF IRON-OXO CLUSTERS IN FATTY ACID DESATURATIONR01GM050853 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G. · 1995 to 2007
$1.9M
Investigation of the Proposed 'Half-of-the-Sites' Reactivity of Soluble acyl-ACPF32GM074385 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PIERCE, BRAD S · 2005 to 2006
$93k
NHGRI NIH HHS HG002760NIGMS NIH HHS F32 GM074385NIGMS NIH HHS GM50853NIGMS NIH HHS P50 GM064598NIGMS NIH HHS U54 GM074901NLM NIH HHS LM007359
6 · The paper itself

Abstract

The Center for Eukaryotic Structural Genomics (CESG) produces and solves the structures of proteins from eukaryotes. We have developed and operate a pipeline to both solve structures and to test new methodologies. Both NMR and X-ray crystallography methods are used for structure solution. CESG chooses targets based on sequence dissimilarity to known structures, medical relevance, and nominations from members of the scientific community. Many times proteins qualify in more than one of these categories. Here we review some of the structures that have connections to human health and disease.

Indexed as

GenomicsCrystallography, X-RayHumansNuclear Magnetic Resonance, BiomolecularProteinsProteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.