ArticleSkeletal radiology2007
Optimization of b value in diffusion-weighted MRI for the differential diagnosis of benign and malignant vertebral fractures.
Article in Skeletal radiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- ADC as a useful diagnostic tool for differentiating benign and malignant vertebral bone marrow lesions and compression fractures: a systematic review and meta-analysis.European radiology · 2018Pooled it
- Standard-b-value vs low-b-value DWI for differentiation of benign and malignant vertebral fractures: a meta-analysis.The British journal of radiology · 2016Pooled it
- SSH-EPI diffusion-weighted MR imaging of the spine with low b values: is it useful in differentiating malignant metastatic tumor infiltration from benign fracture edema?Skeletal radiology · 2009Trial
- Assessing Lumbar Spine Microstructure in Osteoporosis Using IVIM-DWI and IDEAL-IQ Sequences.Clinical interventions in aging · 2025Article
- Correlation between Vertebral Marrow Fat Fraction in MRI Using DIXON Technique and BMD in DXA in Patients of Suspected Osteoporosis.The Indian journal of radiology & imaging · 2024Article
- [Diffusion-Weighted Magnetic Resonance Imaging of Spine].Taehan Yongsang Uihakhoe chi · 2020Review
- Review of the Imaging Features of Benign Osteoporotic and Malignant Vertebral Compression Fractures.AJNR. American journal of neuroradiology · 2018Review
- Evaluation of Apparent Diffusion Coefficient Values in Spinal Tuberculosis by MRI.Journal of clinical and diagnostic research : JCDR · 2016Article
- Parameter Estimation Error Dependency on the Acquisition Protocol in Diffusion Kurtosis Imaging.Applied magnetic resonance · 2016Article
- Estimation of optimal b-value sets for obtaining apparent diffusion coefficient free from perfusion in non-small cell lung cancer.Physics in medicine and biology · 2015Article
- Evaluation of MR Spectroscopy and Diffusion-Weighted MRI in Postmenopausal Bone Strength.Cureus · 2015Article
- [Differentiation between acute osteoporotic and metastatic vertebral body fractures by imaging].Der Unfallchirurg · 2015Article
- Clinical evaluation of reduced field-of-view diffusion-weighted imaging of the cervical and thoracic spine and spinal cord.AJNR. American journal of neuroradiology · 2012Article
- Diffusion-weighted imaging (DWI) in musculoskeletal MRI: a critical review.Skeletal radiology · 2011Review
- Multiparameter MRI assessment of normal-appearing and diseased vertebral bone marrow.European radiology · 2010Article
- Single-Shot Echo-Planar Diffusion-Weighted MR Imaging at 3T and 1.5T for Differentiation of Benign Vertebral Fracture Edema and Tumor Infiltration.Korean journal of radiologyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective was to explore the optimal b value in diffusion-weighted imaging (DWI) of MRI for differential diagnosis of benign and malignant vertebral fractures. MATERIALS AND
methodsThirty-four consecutive patients with vertebral compression fractures underwent sagittal diffusion-weighted imaging (DWI) with different b values. The group included 14 patients with 18 benign vertebral fractures due to osteoporosis and/or trauma and 20 patients with 27 malignant vertebral fractures due to malignancy. The quality of the images was analyzed qualitatively on a three-point scale and quantitatively by measurement of the signal-to-noise ratio (SNR). Apparent diffusion coefficient (ADC) values were also calculated.
resultsSmaller b values correlated with better DW image quality. We found significant differences in the qualitative points values among the DW images with different b values (F=302.18, p<0.001). The mean SNR of the images ranged from 21.75+/-3.64 at a b value of 0 s/mm2 to 5.31+/-3.17 at a b value of 800 s/mm2. The SNR of DWI with a b value of 300 s/mm2 (18.62+/-2.47) was significantly different from that with other b values (p<0.01). The mean combined ADC values of malignant fractures were significantly lower than those of benign ones on DWI with a b value of 300 s/mm2 (t=9.097, p<0.01). Four cases of benign vertebral fractures were misdiagnosed as being malignant when b values of 0 s/mm2 and 100 s/mm2 were used.
conclusionsWhen DWI with multiple b values is used to differentiate benign from malignant vertebral compression fractures, b values within the range of around 300 s/mm2 are recommended, taking into account both SNR and diffusion weighting of water molecules.
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