Evidence map›Paper›PMID 17786233›Full record

ArticleThe Journal of clinical investigation2007

Deepening our understanding of immune sentinels in the skin.

Frank O Nestle, Brian J Nickoloff

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of clinical investigation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. How to Build Live-Cell Sensor Microdevices.Sensors (Basel, Switzerland) · 2023
    Article
  3. Changes of Langerhans cells during skin ageing.Postepy dermatologii i alergologii · 2017
    Article
  4. Article
  5. Article
  6. [Immunosenescence and vaccinations in the elderly].Medizinische Klinik (Munich, Germany : 1983) · 2010
    Review
  7. Skin immune sentinels in health and disease.Nature reviews. Immunology · 2009
    Review
  8. Article
  9. Article
  10. HIV infection of the genital mucosa in women.Current HIV/AIDS reports · 2009
    Review
  11. Microneedle-based vaccines.Current topics in microbiology and immunology · 2009
    Review
  12. Article
  13. Setting the stage: host invasion by HIV.Nature reviews. Immunology · 2008
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Frank O NestleSt. John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine, London, United Kingdom. frank.nestle@kcl.ac.uk
Brian J Nickoloff
King's College School · GB

Funding

TUMOR VACCINES AND BONE MARROW TRANSPLANTATIONP01CA039542 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JAMES L. M. FERRARA · 1985 to 2026
$47.9M
ROLE OF ADHESION MOLECULES IM PSORIASISR01AR040065 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NICKOLOFF, BRIAN J · 1989 to 2009
$2.7M
NCI NIH HHS CA39542NCI NIH HHS P01 CA039542NIAMS NIH HHS AR40065NIAMS NIH HHS R01 AR040065Wellcome Trust
6 · The paper itself

Abstract

Advances in our understanding of the skin immune system have a major impact on studies of skin autoimmunity, graft-versus-host disease, inflammation, and cancer as well as on the development of novel vaccines and immunotherapy approaches. In this issue of the JCI, Zaba et al. carefully dissected the complex network of DCs and macrophages residing in normal human skin and defined novel phenotypic markers for these immunocytes (see the related article beginning on page 2517). These studies provide the basis for better insight into the role of important immune sentinels contributing to the maintenance of skin tissue homeostasis and lay the foundation for future studies of the skin immune system.

Indexed as

AnimalsDendritic CellsHumansMacrophagesSignal TransductionSkin

Identifiers

PMID17786233
PMCPMC1952646
OpenAlexW2083072666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.