Evidence map›Paper›PMID 17786201›Full record

ArticlePloS one2007

Beringian standstill and spread of Native American founders.

Erika Tamm, Toomas Kivisild, Maere Reidla, Mait Metspalu, David Glenn Smith, Connie J Mulligan, Claudio M Bravi, Olga Rickards, Cristina Martinez-Labarga, Elsa K Khusnutdinova and 11 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 187 papers.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed
16.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 695 citations in OpenAlex.

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  9. TheScience (New York, N.Y.) · 2025
    Article
  10. Article
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  12. Founder effects identify languages of the earliest Americans.American journal of biological anthropology · 2025
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127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 6 countries.

Erika TammDepartment of Evolutionary Biology, University of Tartu, Estonian Biocentre, Tartu, Estonia.
Toomas Kivisild
Maere Reidla
Mait Metspalu
David Glenn Smith
Connie J Mulligan
Claudio M Bravi
Olga Rickards
Cristina Martinez-Labarga
Elsa K Khusnutdinova
Sardana A Fedorova
Maria V Golubenko
Vadim A Stepanov
Marina A Gubina
Sergey I Zhadanov
Ludmila P Ossipova
Larisa Damba
Mikhail I Voevoda
Jose E Dipierri
Richard Villems
Ripan S Malhi
University of Tartu · EEEstonian Biocentre · EEInstitute of Cytology and Genetics · RUUniversity of Rome Tor Vergata · ITInstituto Multidisciplinario de Biología Celular · ARLeverhulme Trust · GBNational University of Jujuy · ARResearch Institute of Medical Genetics of Russian Academy of Medical Sciences · RURussian Academy of Sciences · RUUniversity of California, Davis · USUniversity of Florida · USUniversity of Illinois Urbana-Champaign · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Native Americans derive from a small number of Asian founders who likely arrived to the Americas via Beringia. However, additional details about the initial colonization of the Americas remain unclear. To investigate the pioneering phase in the Americas we analyzed a total of 623 complete mtDNAs from the Americas and Asia, including 20 new complete mtDNAs from the Americas and seven from Asia. This sequence data was used to direct high-resolution genotyping from 20 American and 26 Asian populations. Here we describe more genetic diversity within the founder population than was previously reported. The newly resolved phylogenetic structure suggests that ancestors of Native Americans paused when they reached Beringia, during which time New World founder lineages differentiated from their Asian sister-clades. This pause in movement was followed by a swift migration southward that distributed the founder types all the way to South America. The data also suggest more recent bi-directional gene flow between Siberia and the North American Arctic.

Indexed as

Indians, North AmericanAsiaDNA, MitochondrialGenotypeHaplotypesHumansMutationPhylogenyDNA, Mitochondrial

Identifiers

PMID17786201
PMCPMC1952074
OpenAlexW2109701276

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.