ReviewEuropean journal of pediatrics2008
Assessment of febrile seizures in children.
Review in European journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.
- Risk of bacterial meningitis in young children with a first seizure in the context of fever: a systematic review and meta-analysis.PloS one · 2013Pooled it
- Copeptin as a serum biomarker of febrile seizures.PloS one · 2015Trial
- Etiology and short-term outcome of pediatric coma at a tertiary hospital in Douala, Cameroon.BMC pediatrics · 2025Article
- Determining Pro-oxidant Antioxidant Balance in Febrile Children With and Without Seizure: A Comparative Study.Basic and clinical neuroscience · 2025Article
- Risk factors and predictors of recurrence of febrile seizures in children in Nantong, China: a retrospective cohort study.BMC pediatrics · 2024Article
- Clinical manifestations and EEG findings in children infected with COVID-19 and exhibiting neurological symptoms.BMC pediatrics · 2024Article
- Serum level of vitamin A in febrile children with and without seizure: A comparative study.Heliyon · 2023Article
- Management of children with febrile seizures: a Greek nationwide survey.European journal of pediatrics · 2023Article
- Evaluation of patients presenting with febrile seizures in an Iranian referral hospital: emphasis on the frequency of meningitis and co-infections.BMC pediatrics · 2023Article
- Depressive, Anxiety, and Stress Symptoms in Parents of Children Being Admitted for Febrile Seizures in a Tertiary Hospital in the East Coast of Malaysia.European journal of investigation in health, psychology and education · 2023Article
- The role of fever in febrile seizures: major implications for fever perception.Frontiers in pediatrics · 2023Article
- Comparing the effect of intermittent diazepam and continuous phenobarbital in preventing recurrent febrile seizures among children under 6 years old: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Review
- Etiological and risk factors in recurrent febrile seizures: Insights through EEG analysis.Qatar medical journal · 2023Article
- Febrile seizures: A review.Journal of the American College of Emergency Physicians open · 2022Review
- Korean Childcare Providers' Knowledge, Attitudes, Concerns, and Practices of Febrile Convulsions.International journal of environmental research and public health · 2021Article
- Exploring Variances of White Matter Integrity and the Glymphatic System in Simple Febrile Seizures and Epilepsy.Frontiers in neurology · 2021Article
- Identification of MissenseChildren (Basel, Switzerland) · 2020Article
- Is There Any Need for Emergency Neuroimaging in Children With first Complex Febrile Seizure?Iranian journal of child neurology · 2020Article
- Article
- Oral Diazepam in Febrile Seizures Following Acellular Pertussis Vaccination.Advanced biomedical research · 2019Article
Corrections and comments
- Commented on by
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Febrile seizures are the most common form of childhood seizures, affecting 2-5% of all children and usually appearing between 3 months and 5 years of age. Despite its predominantly benign nature, a febrile seizure (FS) is a terrifying experience for most parents. The condition is perhaps one of the most prevalent causes of admittance to pediatric emergency wards worldwide. FS, defined as either simple or complex, may be provoked by any febrile bacterial or (more usually) viral illness. No specific level of fever is required to diagnose FS. It is essential to exclude underlying meningitis in all children with FS, either clinically or, if any doubt remains, by lumbar puncture. There is no evidence, however, to support routine lumbar puncture in all children admitted with simple FS, especially when typical clinical signs of meningitis are lacking. The risk of epilepsy following FS is 1-6%. The association, however small, between FS and epilepsy may demonstrate a genetic link between FS and epilepsy rather than a cause and effect relationship. The effectiveness of prophylactic treatment with medication remains controversial. There is no evidence of the effectiveness of antipyretics in preventing future FS. Prophylactic use of paracetamol, ibuprofen or a combination of both in FS, is thus a questionable practice. There is reason to believe that children who have experienced a simple FS are over-investigated and over-treated. This review aims to provide physicians with adequate knowledge to make rational assessments of children with febrile seizures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.