Evidence map›Paper›PMID 17764925›Full record

ReviewCurrent opinion in structural biology2007

Secretion machinery at the cell plasma membrane.

Bhanu P Jena

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. NeuronalJournal of molecular structure · 2014
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Porosome in astrocytes.Journal of cellular and molecular medicine · 2009
    Article
  15. Article
  16. Cell secretion: an update.Journal of cellular and molecular medicine · 2008
    Review
  17. Porosome in Cystic Fibrosis.Discoveries (Craiova, Romania)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bhanu P JenaDepartment of Physiology, Wayne State University School of Medicine, 5245 Scott Hall, 540 E. Canfield Avenue, Detroit, MI 48201-4177, USA. bjena@med.wayne.edu

Funding

UNDERSTANDING MEMBRANE FUSION A BIOENGINEERING APPROACHR01EB000303 · NIBIB · WAYNE STATE UNIVERSITY · PI JENA, BHANU P · 2002 to 2004
$1.2M
EXOCYTOSIS: USING NANOSURGERY AND BIOENGINEERINGR01DK056212 · NIDDK · YALE UNIVERSITY · PI JENA, BHANU P · 1999 to 2003
$1.1M
UNDERSTANDING MEMBRANE FUSION A BIOENGINEERING APPROACHR01NS039918 · NINDS · YALE UNIVERSITY · PI JENA, BHANU P · 2000 to 2001
$791k
NIBIB NIH HHS R01 EB000303NIDDK NIH HHS DK-56212NIDDK NIH HHS R01 DK056212NINDS NIH HHS NS-39918NINDS NIH HHS R01 NS039918
6 · The paper itself

Abstract

Secretion is a fundamental cellular process involving the regulated release of intracellular products from cells. Physiological functions such as neurotransmission, or the release of hormones and digestive enzymes, are all governed by cell secretion. Three critical activities occur at the cell plasma membrane to ensure secretion. Membrane-bound secretory vesicles dock, fuse, and expel their contents to the outside via specialized and permanent plasma membrane structures, called porosomes or fusion pores. In recent years, significant progress has been made in our understanding of these three key cellular activities required for cell secretion. The molecular machinery and mechanism involving them is summarized in this article.

Indexed as

AnimalsCell MembraneHumansMembrane FusionMicroscopy, Atomic ForceMicroscopy, ElectronSecretory Vesicles

Identifiers

PMID17764925
PMCPMC2075359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.