ArticlePhysiology & behavior2008
Amino acid and carbohydrate preferences in C57BL/6ByJ and 129P3/J mice.
Article in Physiology & behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Altered salt taste response and increased tongue epithelium Scnna1 expression in adult Engrailed-2 null mice.Physiology & behavior · 2018Article
- Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Detection of maltodextrin and its discrimination from sucrose are independent of the T1R2 + T1R3 heterodimer.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Genetics of Amino Acid Taste and Appetite.Advances in nutrition (Bethesda, Md.) · 2016Review
- Regulation of bitter taste responses by tumor necrosis factor.Brain, behavior, and immunity · 2015Article
- Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains.Physiology & behavior · 2014Article
- Enantiomer-specific selection of amino acids.Amino acids · 2013Article
- Impact of T1r3 and Trpm5 on carbohydrate preference and acceptance in C57BL/6 mice.Chemical senses · 2013Article
- The functional role of the T1R family of receptors in sweet taste and feeding.Physiology & behavior · 2011Review
- Citric acid and quinine share perceived chemosensory features making oral discrimination difficult in C57BL/6J mice.Chemical senses · 2011Article
- Dietary proteins and food-related reward signals.Food & nutrition research · 2011Article
- Taste does not determine daily intake of dilute sugar solutions in mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2010Article
- Nutrient selection in the absence of taste receptor signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Glutamate taste and appetite in laboratory mice: physiologic and genetic analyses.The American journal of clinical nutrition · 2009Review
- T1R3 taste receptor is critical for sucrose but not Polycose taste.American journal of physiology. Regulatory, integrative and comparative physiology · 2009Article
- Greater superficial petrosal nerve transection in rats does not change unconditioned licking responses to putatively sweet taste stimuli.Chemical senses · 2008Article
- Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.Physiological genomics · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Compared with mice from the 129P3/J (129) inbred strain, mice from the C57BL/6ByJ (B6) inbred strain have higher consumption of several sweet-tasting amino acids and carbohydrates. To examine the relative contribution of taste and nutritive properties in these strain differences, we measured responses of B6 and 129 mice to eight sweet and non-sweet amino acids and carbohydrates in two-bottle preference tests with water. Mice from the two strains did not differ in consumption of non-sweet l-valine and l-histidine. Compared with 129 mice, B6 mice had higher consumption and lower preference thresholds for sweet amino acids l-glutamine, l-alanine and l-threonine, monosaccharides glucose and fructose, and maltooligosaccharide. These data suggest that differences in gustatory responsiveness are an important factor underlying higher consumption of some amino acids and carbohydrates by B6 mice compared with 129 mice. It is likely that in B6 mice, higher sweet taste responsiveness results in increased consumption of sweet-tasting amino acids and sugars, and higher taste responsiveness to complex carbohydrates results in increased consumption of maltooligosaccharide. However, postingestive processes also influence nutrient consumption and may be responsible for higher intake of carbohydrates compared with sweet-tasting amino acids. Results of this study set the stage for genetic analysis of differences between B6 and 129 mice in taste responsiveness and macronutrient consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.