ReviewPediatric cardiology
Medical management of the failing Fontan.
Review in Pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Meta-analysis of Fontan procedure : Extracardiac conduit vs. intracardiac lateral tunnel.Herz · 2018Pooled it
- Urinary Extracellular Vesicle Analysis Reveals Early Signs of Kidney Inflammation and Damage in Single Ventricle Paediatric Patients After Fontan Operation.International journal of nanomedicine · 2025Article
- Patient-specific closed-loop model of the fontan circulation: Calibration and validation.Heliyon · 2024Article
- Comparative Metabolomics in Single Ventricle Patients after Fontan Palliation: A Strong Case for a Targeted Metabolic Therapy.Metabolites · 2023Review
- Current diagnostic and therapeutic strategies for the management of lymphatic insufficiency in patients with hypoplastic left heart syndrome.Frontiers in pediatrics · 2023Review
- Heart Failure in Complex Congenital Heart Disease of the Adult.Current cardiology reports · 2022Review
- Long-term management of Fontan patients: The importance of a multidisciplinary approach.Frontiers in pediatrics · 2022Review
- Management of circulatory failure after Fontan surgery.Frontiers in pediatrics · 2022Review
- Functional hepatic deterioration determined byFrontiers in cardiovascular medicine · 2022Article
- Current Treatment Options for the Failing Fontan Circulation.Current cardiology reviews · 2022Review
- The failing Fontan.Indian journal of thoracic and cardiovascular surgery · 2021Review
- Morphologic Alterations Precede Functional Hepatic Impairment as Determined byFrontiers in cardiovascular medicine · 2021Article
- Mechanical Circulatory Support for Single Ventricle Failure.Frontiers in cardiovascular medicine · 2018Review
- Long term negative pressure ventilation: Rescue for the failing fontan?World journal of cardiology · 2014Review
- The relationship of patient medical and laboratory characteristics to changes in functional health status in children and adolescents after the Fontan procedure.Pediatric cardiology · 2014Article
- Extracardiac complications of the Fontan circuit.Pediatric radiology · 2012Review
- Protein losing enteropathy secondary to a pulmonary artery stent.Annals of pediatric cardiology · 2012Article
- Orthotopic heart transplantation in patients with univentricular physiology.Current cardiology reviews · 2011Review
- Anesthetic management of noncardiac surgery for patients with single ventricle physiology.Journal of anesthesia · 2011Review
- The Fontan patient: inconsistencies in medication therapy across seven pediatric heart network centers.Pediatric cardiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Fontan operation accomplishes complete separation of systemic venous blood from pulmonary venous circulation in patients with single ventricle anatomy. Operative survival since the first description of the Fontan operation is excellent in the current era through modifications in surgical techniques, identification of patient-specific risk factors, and advances in postoperative care. Improved early outcomes have also resulted in a decline in late mortality for patients who have undergone staged palliation with the Fontan operation. As the number of late survivors from the Fontan operation increases, caregivers will be evermore faced with the challenge of recognizing and managing the patient with failing Fontan physiology. Even after excellent early results, patients with single ventricle lesions remain at risk of progressive ventricular dysfunction, dysrhythmias, progressive hypoxemia, elevated pulmonary vascular resistance, and protein-losing enteropathy, which can result in morbidities including but not limited to, myocardial failure, thromboembolism, and stroke. Consequently, continued long-term survival of patients who undergo the Fontan operation is dependent upon preservation of single ventricle function, avoidance of late complications, and, in the patient with a failing Fontan, recognition and treatment of the underlying pathophysiologic process that has resulted in Fontan failure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.