ArticleLearning & memory (Cold Spring Harbor, N.Y.)2007
Control of appetitive and aversive taste-reactivity responses by an auditory conditioned stimulus in a devaluation task: a FOS and behavioral analysis.
Article in Learning & memory (Cold Spring Harbor, N.Y.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation.Proceedings of the National Academy of Sciences of the United States of America · 2009Trial
- Contribution of Rat Insular Cortex to Stimulus-Guided Action.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation.Brain : a journal of neurology · 2023Article
- Targeted effects of ketamine on perceptual expectation during mediated learning in rats.Psychopharmacology · 2022Article
- Threat and Bidirectional Valence Signaling in the Nucleus Accumbens Core.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Using internal memory representations in associative learning to study hallucination-like phenomenon.Neurobiology of learning and memory · 2020Review
- Differential rearing alters taste reactivity to ethanol, sucrose, and quinine.Psychopharmacology · 2020Article
- Assessing Reality Testing in Mice Through Dopamine-Dependent Associatively Evoked Processing of Absent Gustatory Stimuli.Schizophrenia bulletin · 2020Article
- PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice.Brain and behavior · 2020Article
- Contributions of Pavlovian incentive motivation to cue-potentiated feeding.Scientific reports · 2018Article
- Examining the influence of CS duration and US density on cue-potentiated feeding through analyses of licking microstructure.Learning and motivation · 2018Article
- Opposing Roles of Rapid Dopamine Signaling Across the Rostral-Caudal Axis of the Nucleus Accumbens Shell in Drug-Induced Negative Affect.Biological psychiatry · 2017Article
- Explicit and implicit emotion regulation: a multi-level framework.Social cognitive and affective neuroscience · 2017Review
- Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats.Journal of visualized experiments : JoVE · 2016Article
- Nucleus Accumbens Core and Shell Differentially Encode Reward-Associated Cues after Reinforcer Devaluation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Impaired Reality Testing in Mice Lacking Phospholipase Cβ1: Observed by Persistent Representation-Mediated Taste Aversion.PloS one · 2016Article
- Prior extended daily access to cocaine elevates the reward threshold in a conditioned place preference test.Addiction biology · 2014Article
- Differential effects of acute and repeated stress on hippocampus and amygdala inputs to the nucleus accumbens shell.The international journal of neuropsychopharmacology · 2013Article
- Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption.Biological psychiatry · 2013Article
- Neural processing of gustatory information in insular circuits.Current opinion in neurobiology · 2012Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Through associative learning, cues for biologically significant reinforcers such as food may gain access to mental representations of those reinforcers. Here, we used devaluation procedures, behavioral assessment of hedonic taste-reactivity responses, and measurement of immediate-early gene (IEG) expression to show that a cue for food engages behavior and brain activity related to sensory and hedonic processing of that food. Rats first received a tone paired with intraoral infusion of sucrose. Then, in the absence of the tone, the value of sucrose was reduced (Devalue group) by pairing sucrose with lithium chloride (LiCl), or maintained (Maintain group) by presenting sucrose and LiCl unpaired. Finally, taste-reactivity responses to the tone were assessed in the absence of sucrose. Devalue rats showed high levels of aversive responses and minimal appetitive responses, whereas Maintain rats exhibited substantial appetitive responding but little aversive responding. Control rats that had not received tone-sucrose pairings did not display either class of behaviors. Devalue rats showed greater FOS expression than Maintain rats in several brain regions implicated in devaluation task performance and the display of aversive responses, including the basolateral amygdala, orbitofrontal cortex, gustatory cortex (GC), and the posterior accumbens shell (ACBs), whereas the opposite pattern was found in the anterior ACBs. Both Devalue and Maintain rats showed greater FOS expression than control rats in amygdala central nucleus, GC, and both subregions of ACBs. Thus, through associative learning, auditory cues for food gained access to neural processing in several brain regions importantly involved in the processing of taste memory information.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.