ReviewJournal of cellular and molecular medicine
Mast cells in vulnerable atherosclerotic plaques--a view to a kill.
Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Article
- Cardiovascular manifestations in mast cell activation disease: key insights for cardiologists and angiologists.Frontiers in cardiovascular medicine · 2025Review
- Micro- and Macrovascular Effects of Inflammation in Peripheral Artery Disease-Pathophysiology and Translational Therapeutic Approaches.Biomedicines · 2023Review
- Review
- Acute and Chronic Effects of Cocaine on Cardiovascular Health.International journal of molecular sciences · 2019Review
- Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease.Cardiology journal · 2019Article
- New Insights into the Role of Inflammation in the Pathogenesis of Atherosclerosis.International journal of molecular sciences · 2017Review
- Elevated Adiponectin Levels Suppress Perivascular and Aortic Inflammation and Prevent AngII-induced Advanced Abdominal Aortic Aneurysms.Scientific reports · 2016Article
- Serum tryptase detected during acute coronary syndrome is significantly related to the development of major adverse cardiovascular events after 2 years.Clinical and molecular allergy : CMA · 2015Article
- Cathepsin G activity lowers plasma LDL and reduces atherosclerosis.Biochimica et biophysica acta · 2014Article
- Glucagon effects on 3H-histamine uptake by the isolated guinea-pig heart during anaphylaxis.BioMed research international · 2014Article
- Mast cell chymase and tryptase as targets for cardiovascular and metabolic diseases.Current pharmaceutical design · 2013Review
- Correlation of lifetime progress of atherosclerosis and morphologic markers of severity in humans: new tools for a more sensitive evaluation.Clinics (Sao Paulo, Brazil) · 2012Article
- Comparison between the collagen intensity and mast cell density in the lingual muscles and myocardium of autopsied chronic chagasic and nonchagasic patients.Parasitology research · 2012Article
- Probiotic Lactobacillus rhamnosus downregulates FCER1 and HRH4 expression in human mast cells.World journal of gastroenterology · 2011Article
- Mountain cedar pollen induces IgE-independent mast cell degranulation, IL-4 production, and intracellular reactive oxygen species generation.Cellular immunology · 2011Article
- Histamine blood concentration in ischemic heart disease patients.Journal of biomedicine & biotechnology · 2011Article
- Ischemia/reperfusion injury: The role of immune cells.World journal of cardiology · 2010Article
- "Gum bug, leave my heart alone!"--epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis.Journal of dental research · 2010Review
- Endogenous suppression of mast cell development and survival by IL-4 and IL-10.Journal of leukocyte biology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present review is to discuss the participation of mast cells in the pathogenesis of erosion and rupture of atherosclerotic plaques, the major causes behind acute coronary syndromes and myocardial infarction. We present ex vivo observations describing mast cells and their activation in human atherosclerotic plaques and discuss in vitro and in vivo data showing that mast cells are potential regulators of inflammation, immunity and adverse remodeling, including matrix remodeling and cell death. Furthermore, we focus on studies that have been performed with human tissues and human mast cells, but when appropriate, we also discuss observations made in animal models. Finally, we present potential pharmacological means to modulate mast cell responses in the arterial vessel walls.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.