ArticleJournal of molecular evolution1991
Structural and phylogenetic analysis of the chicken ventricular myosin heavy chain rod.
Article in Journal of molecular evolution, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 25 citations in OpenAlex.
- Dual function of the UNC-45b chaperone with myosin and GATA4 in cardiac development.Journal of cell science · 2012Article
- Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.The Journal of physiology · 2010Article
- Evidence for distinct fast and slow myogenic cell lineages in human foetal skeletal muscle.Journal of muscle research and cell motility · 1998Article
- Strong evolutionary conservation of broadly expressed protein isoforms in the troponin I gene family and other vertebrate gene families.Journal of molecular evolution · 1996Article
- Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- The evolutionary relationship of avian and mammalian myosin heavy-chain genes.Journal of molecular evolution · 1993Article
- New nucleotide sequence data on the EMBL File Server.Nucleic acids research · 1992Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We have isolated and characterized five overlapping clones that encompass 3.2 kb and encode a part of the short subfragment 2, the hinge, and the light meromyosin regions of the myosin heavy chain rod as well as 143 bp of the 3' untranslated portion of the mRNA. Northern blot analysis showed expression of this mRNA mainly in ventricular muscle of the adult chicken heart, with trace levels detected in the atrium. Transient expression was seen in skeletal muscle during development and in regenerating skeletal muscle following freeze injury. To our knowledge, this is the first report of an avian ventricular myosin heavy chain sequence. Phylogenetic analysis indicated that this isoform is a distant homolog of other ventricular and skeletal muscle myosin heavy chains and represents a distinct member of the multigene family of sarcomeric myosin heavy chains. The ventricular myosin heavy chain of the chicken is either paralogous to its counterpart in other vertebrates or has diverged at a significantly higher rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.