Evidence map›Paper›PMID 17729394›Full record

ReviewWorld journal of gastroenterology2007

Liver iron transport.

Ross-M Graham, Anita-C-G Chua, Carly-E Herbison, John-K Olynyk, Debbie Trinder

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 201 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The role of ferroptosis in DM-induced liver injury.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  9. Article
  10. Article
  11. Elucidating Iron Metabolism through Molecular Imaging.Current issues in molecular biology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. SIgA in various pulmonary diseases.European journal of medical research · 2023
    Review
  16. Mitochondrial Regulation of Ferroptosis in Cancer Therapy.International journal of molecular sciences · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. The Emerging Roles of Ferroptosis in Neonatal Diseases.Journal of inflammation research · 2023
    Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ross-M GrahamSchool of Medicine and Pharmacology, Fremantle Hospital, University of Western Australia, PO Box 480, Fremantle 6959, Western Australia, Australia.
Anita-C-G Chua
Carly-E Herbison
John-K Olynyk
Debbie Trinder
Fremantle Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liver plays a central role in iron metabolism. It is the major storage site for iron and also expresses a complex range of molecules which are involved in iron transport and regulation of iron homeostasis. An increasing number of genes associated with hepatic iron transport or regulation have been identified. These include transferrin receptors (TFR1 and 2), a ferrireductase (STEAP3), the transporters divalent metal transporter-1 (DMT1) and ferroportin (FPN) as well as the haemochromatosis protein, HFE and haemojuvelin (HJV), which are signalling molecules. Many of these genes also participate in iron regulatory pathways which focus on the hepatic peptide hepcidin. However, we are still only beginning to understand the complex interactions between liver iron transport and iron homeostasis. This review outlines our current knowledge of molecules of iron metabolism and their roles in iron transport and regulation of iron homeostasis.

Indexed as

Biological TransportHomeostasisHumansIronKupffer CellsLiverIron

Identifiers

PMID17729394
PMCPMC4611194
OpenAlexW2102859818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.