ReviewWorld journal of gastroenterology2007
Non-HFE haemochromatosis.
Review in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.
- A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.Nature genetics · 2009Pooled it
- Macrophagic myofasciitis associated with transferrin receptor 2 and solute carrier family 40 member 1 variants and iron dysregulation: a case report.Journal of medical case reports · 2026Article
- Unraveling genotype-phenotype relationships in hereditary hemochromatosis through integrated biobank data analysis.BMC genomics · 2026Article
- A Review of New Concepts in Iron Overload.Gastroenterology & hepatology · 2024Article
- Cardiac Amyloidosis Versus Other Restrictive Cardiomyopathies: A Retrospective Analysis of Cardiovascular Outcomes and Arrhythmic Burden.Clinical Medicine Insights. Cardiology · 2024Article
- Hyperferritinemia-A Clinical Overview.Journal of clinical medicine · 2021Review
- Intersection of Iron and Copper Metabolism in the Mammalian Intestine and Liver.Comprehensive Physiology · 2018Review
- Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading.Human genomics · 2018Article
- Juvenile hemochromatosis:World journal of clinical cases · 2017Article
- Pathophysiological consequences and benefits ofHaematologica · 2017Review
- Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model.Journal of gastroenterology · 2017Article
- The global prevalence of HFE and non-HFE hemochromatosis estimated from analysis of next-generation sequencing data.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- The Regulation of Iron Absorption and Homeostasis.The Clinical biochemist. Reviews · 2016Review
- Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis.Investigative ophthalmology & visual science · 2016Article
- Mechanistic and regulatory aspects of intestinal iron absorption.American journal of physiology. Gastrointestinal and liver physiology · 2014Review
- The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.Investigative ophthalmology & visual science · 2014Article
- Iron metabolism: from health to disease.Journal of clinical laboratory analysis · 2014Review
- Telomere length and elevated iron: the influence of phenotype and HFE genotype.American journal of hematology · 2013Article
- Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells.Investigative ophthalmology & visual science · 2013Article
- Iranian hereditary hemochromatosis patients: baseline characteristics, laboratory data and gene mutations.Medical science monitor : international medical journal of experimental and clinical research · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis is an autosomal recessive disorder and can be caused by mutations in either hemojuvelin or hepcidin. An adult onset form of HH similar to HFE-HH is caused by homozygosity for mutations in transferrin receptor 2. The autosomal dominant iron overload disorder ferroportin disease is caused by mutations in the iron exporter ferroportin. The clinical characteristics and molecular basis of the various types of non-HFE haemochromatosis are reviewed. The study of these disorders and the molecules involved has been invaluable in improving our understanding of the mechanisms involved in the regulation of iron metabolism.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.