Trial reportThe American journal of psychiatry2007
Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial.
Trial report in The American journal of psychiatry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 7 syntheses or guidelines pooled it, 272 citations in OpenAlex.
- Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024Pooled it
- The impact of treating parental bipolar disorder and schizophrenia on their children's mental health and wellbeing: an empty systematic review.Frontiers in psychiatry · 2024Pooled it
- Digital biomarkers from geolocation data in bipolar disorder and schizophrenia: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2019Pooled it
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.Bipolar disorders · 2018Guideline
- Efficacy of cognitive-behavioral therapy in patients with bipolar disorder: A meta-analysis of randomized controlled trials.PloS one · 2017Pooled it
- New modalities of assessment and treatment planning in depression: the sequential approach.CNS drugs · 2010Pooled it
- Psychoeducation for depression, anxiety and psychological distress: a meta-analysis.BMC medicine · 2009Pooled it
- Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions.Journal of affective disorders · 2017Trial
- Trial
- A cluster analytic approach to identifying predictors and moderators of psychosocial treatment for bipolar depression: Results from STEP-BD.Journal of affective disorders · 2016Trial
- Effects on health-related quality of life in patients treated with lurasidone for bipolar depression: results from two placebo controlled bipolar depression trials.BMC psychiatry · 2016Trial
- Family-focused therapy for individuals at clinical high risk for psychosis: treatment fidelity within a multisite randomized trial.Early intervention in psychiatry · 2016Trial
- Trial
- Age at onset, course of illness and response to psychotherapy in bipolar disorder: results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).Psychological medicine · 2014Trial
- Pharmacotherapy and family-focused treatment for adolescents with bipolar I and II disorders: a 2-year randomized trial.The American journal of psychiatry · 2014Trial
- Extreme attributions predict the course of bipolar depression: results from the STEP-BD randomized controlled trial of psychosocial treatment.The Journal of clinical psychiatry · 2013Trial
- A randomized trial of family focused treatment for adolescents and young adults at risk for psychosis: study rationale, design and methods.Early intervention in psychiatry · 2012Trial
- A randomized pilot study of psychotherapy and quetiapine for the acute treatment of bipolar II depression.Bipolar disorders · 2012Trial
- Mindfulness-based cognitive therapy for nonremitted patients with bipolar disorder.CNS neuroscience & therapeutics · 2012Trial
- Trial
27 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
Abstract
objectivePsychosocial interventions are effective adjuncts to pharmacotherapy in delaying recurrences of bipolar disorder; however, to date their effects on life functioning have been given little attention. In a randomized trial, the authors examined the impact of intensive psychosocial treatment plus pharmacotherapy on the functional outcomes of patients with bipolar disorder over the 9 months following a depressive episode.
methodParticipants were 152 depressed outpatients with bipolar I or bipolar II disorder in the multisite Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study. All patients received pharmacotherapy. Eighty-four patients were randomly assigned to intensive psychosocial intervention (30 sessions over 9 months of interpersonal and social rhythm therapy, cognitive behavior therapy [CBT], or family-focused therapy), and 68 patients were randomly assigned to collaborative care (a 3-session psychoeducational treatment). Independent evaluators rated the four subscales of the Longitudinal Interval Follow-Up Evaluation-Range of Impaired Functioning Tool (LIFE-RIFT) (relationships, satisfaction with activities, work/role functioning, and recreational activities) through structured interviews given at baseline and every 3 months over a 9-month period.
resultsPatients in intensive psychotherapy had better total functioning, relationship functioning, and life satisfaction scores over 9 months than patients in collaborative care, even after pretreatment functioning and concurrent depression scores were covaried. No effects of psychosocial intervention were observed on work/role functioning or recreation scores during this 9-month period.
conclusionsIntensive psychosocial treatment enhances relationship functioning and life satisfaction among patients with bipolar disorder. Alternate interventions focused on the specific cognitive deficits of individuals with bipolar disorder may be necessary to enhance vocational functioning after a depressive episode.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.