Evidence map›Paper›PMID 17726832›Full record

ReviewThe Journal of infectious diseases2007

Treatment Options for HIV-Associated Tuberculosis.

Philip Chukwuka Onyebujoh, Isabela Ribeiro, Christopher Curtis Whalen

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. The impact of alcohol use on tuberculosis treatment outcomes: a systematic review and meta-analysis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020
    Pooled it
  2. Article
  3. Recent advancements in tuberculosis (TB) treatment regimens.Journal of family medicine and primary care · 2025
    Review
  4. Role of therapeutic drug monitoring in the treatment of multi-drug resistant tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Experience with rifabutin replacing rifampin in the treatment of tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2011
    Article
  9. Review
  10. Review
  11. Article
  12. HIV-Associated Tuberculosis.Clinical & developmental immunology · 2011
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Philip Chukwuka OnyebujohUnited Nations Children's Fund/United Nations Development Programme/World Bank/World Health Organization Special Programme for Research and Training in Tropical Diseases, Geneva, Switzerland. onyebujohp@who.int
Isabela Ribeiro
Christopher Curtis Whalen
World Health Organization · CHCase Western Reserve University · US

Funding

HIV/TB in Uganda: Punctuated Antiretroviral TherapyR01AI051219 · NIAID · UNIVERSITY OF GEORGIA · PI WHALEN, CHRISTOPHER C. · 2003 to 2007
$6.1M
NIAID NIH HHS R01 AI051219
6 · The paper itself

Abstract

The vicious interaction between the human immunodeficiency virus (HIV) infection and tuberculosis (TB) pandemics poses special challenges to national control programs and individual physicians. Although recommendations for the treatment of TB in HIV-infected patients do not significantly differ from those for HIV-uninfected patients, the appropriate management of HIV-associated TB is complicated by health system issues, diagnostic difficulties, adherence concerns, overlapping adverse-effect profiles and drug interactions, and the occurrence of paradoxical reactions after the initiation of effective antiretroviral therapy. In this article, recommended treatment strategies and novel approaches to the management of HIV-associated TB are reviewed, including adjuvant treatment and options for treatment simplification. A focused research agenda is proposed in the context of the limitations of the current knowledge framework.

Indexed as

HIVAIDS-Related Opportunistic InfectionsAnti-HIV AgentsAnti-Infective AgentsAntitubercular AgentsBiomedical ResearchClinical Trials as TopicDrug Administration ScheduleHIV InfectionsHumansImmunologic FactorsMicronutrientsTrimethoprim, Sulfamethoxazole Drug CombinationTuberculosisAnti-HIV AgentsAnti-Infective AgentsAntitubercular AgentsImmunologic FactorsMicronutrientsTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID17726832
PMCPMC2860284
OpenAlexW2172255908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.