ArticleNucleic acids research2007
A rapid high-throughput method for the detection and quantification of RNA editing based on high-resolution melting of amplicons.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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Who cites it
80 citing papers in PubMed, 182 citations in OpenAlex.
- Complete assembly of Onobrychis viciifolia mitochondrial genome reveals evolutionary dynamics.Planta · 2026Article
- Rapid and Cost-Effective Digital Quantification of RNA Editing and Maturation in Organelle Transcripts by Oxford Nanopore Target-Indexed-PCR (TIP) Sequencing.Plant direct · 2025Article
- Plant organellar RNA maturation.The Plant cell · 2023Review
- The PPR protein RARE1-mediated editing of chloroplast accD transcripts is required for fatty acid biosynthesis and heat tolerance in Arabidopsis.Plant communications · 2023Article
- RNA Editing in Chloroplast: Advancements and Opportunities.Current issues in molecular biology · 2022Review
- A Comprehensive Evolutionary Study of Chloroplast RNA Editing in Gymnosperms: A Novel Type of G-to-A RNA Editing Is Common in Gymnosperms.International journal of molecular sciences · 2022Article
- Article
- Comprehensive analysis of chloroplast genome of Albizia julibrissin Durazz. (Leguminosae sp.).Planta · 2021Article
- Quantitative Analysis of RNA Editing at Specific Sites in Plant Mitochondria or Chloroplasts Using DNA Sequencing.Bio-protocol · 2021Article
- white panicle2 encoding thioredoxin z, regulates plastid RNA editing by interacting with multiple organellar RNA editing factors in rice.The New phytologist · 2021Article
- A study of RNA-editing inForestry research · 2021Article
- Cytidine-to-Uridine RNA Editing Factor NbMORF8 Negatively Regulates Plant Immunity toPlant physiology · 2020Article
- Light/heat effects on RNA editing in chloroplast NADH-plastoquinone oxidoreductase subunit 2 (ndhB) gene of Calotropis (Calotropis procera).Journal, genetic engineering & biotechnology · 2020Article
- Salinity effects on nad3 gene RNA editing of wild barley mitochondria.Molecular biology reports · 2020Article
- Two organelle RNA recognition motif proteins affect distinct sets of RNA editing sites in thePlant direct · 2020Article
- Article
- Establishment of a Heterologous RNA Editing Event in Chloroplasts.Plant physiology · 2019Article
- MORF9 Functions in Plastid RNA Editing with Tissue Specificity.International journal of molecular sciences · 2019Article
- GUN1 interacts with MORF2 to regulate plastid RNA editing during retrograde signaling.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Biosynthesis of 2-Phenylethanol in Rose Petals Is Linked to the Expression of One Allele ofPlant physiology · 2019Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a rapid, high-throughput method to scan for new RNA editing sites. This method is adapted from high-resolution melting (HRM) analysis of amplicons, a technique used in clinical research to detect mutations in genomes. The assay was validated by the discovery of six new editing sites in different chloroplast transcripts of Arabidopsis thaliana. A screen of a collection of mutants uncovered a mutant defective for editing of one of the newly discovered sites. We successfully adapted the technique to quantify editing of partially edited sites in different individuals or different tissues. This new method will be easily applicable to RNA from any organism and should greatly accelerate the study of the role of RNA editing in physiological processes as diverse as plant development or human health.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.