Evidence map›Paper›PMID 17721792›Full record

ArticleDocumenta ophthalmologica. Advances in ophthalmology2008

Cancer-associated retinopathy (CAR) with electronegative ERG: a case report.

Griet Goetgebuer, Anna-Maria Kestelyn-Stevens, Jean-Jacques De Laey, Philippe Kestelyn, Bart P Leroy

Abstract readCase Reports
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In one paragraph

Article in Documenta ophthalmologica. Advances in ophthalmology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. American journal of ophthalmology case reports · 2024
    Article
  3. Article
  4. Immunotherapy-induced retinopathy mimicking cancer associated retinopathy.American journal of ophthalmology case reports · 2022
    Article
  5. Article
  6. Electroretinographic abnormalities associated with pregabalin: a case report.Documenta ophthalmologica. Advances in ophthalmology · 2020
    Article
  7. Article
  8. Article
  9. Unilateral negative electroretinogram presenting as photophobia.Documenta ophthalmologica. Advances in ophthalmology · 2016
    Article
  10. Article
  11. Article
  12. Article
  13. Negative electroretinograms in the pediatric and adult population.Documenta ophthalmologica. Advances in ophthalmology · 2012
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Griet GoetgebuerDepartment of Ophthalmology, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium.
Anna-Maria Kestelyn-Stevens
Jean-Jacques De Laey
Philippe Kestelyn
Bart P Leroy
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-associated retinopathy (CAR) should be suspected in patients who present with visual symptoms such as rapid unexplained visual loss and seeing shimmering lights, with an abnormal ERG. Electronegative ERG responses are not exclusive to melanoma-associated retinopathy (MAR) but may be seen in CAR as well. We describe a patient with CAR who presented with an electronegative ERG. A 67-year old woman, who presented with complaints of seeing shimmering lights, underwent an extensive ophthalmological and electrophysiological examination. Best-corrected visual acuity was 7/10 in the right and 9/10 in the left eye. Goldmann visual fields showed relative central scotomata and concentric narrowing. Slit-lamp and fundus examination were normal as was fluorescein angiography. Rod-specific ERG responses were severely reduced, with electronegative maximal combined rod-cone responses and delayed cone-responses with normal amplitudes. Melanoma-associated retinopathy was suspected. Extensive dermatological and internal evaluation eventually revealed an oat-cell carcinoma in the right lung. The patient died of pneumonia 2 years after presentation.

Indexed as

AgedCarcinoma, Small CellElectrophysiologyElectroretinographyFatal OutcomeFemaleFluorescein AngiographyHumansLung NeoplasmsParaneoplastic SyndromesRetinal DiseasesScotomaVisual AcuityVisual Fields

Identifiers

PMID17721792
OpenAlexW2016092698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.