Evidence map›Paper›PMID 17720924›Full record

ArticleGenetics2007

Genetic and haplotypic structure in 14 European and African cattle breeds.

Mathieu Gautier, Thomas Faraut, Katayoun Moazami-Goudarzi, Vincent Navratil, Mario Foglio, Cécile Grohs, Anne Boland, Jean-Guillaume Garnier, Didier Boichard, G Mark Lathrop and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 158 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Genome-wide SNP evidence for the genetic uniqueness of indigenous cattle population.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Mathieu GautierINRA, UR339 Laboratoire de Génétique Biochimique et Cytogénétique, F-78350 Jouy-en-Josas, France. mathieu.gautier@jouy.inra.fr
Thomas Faraut
Katayoun Moazami-Goudarzi
Vincent Navratil
Mario Foglio
Cécile Grohs
Anne Boland
Jean-Guillaume Garnier
Didier Boichard
G Mark Lathrop
Ivo G Gut
André Eggen
Département Génétique Animale · FRGenoscope · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRLaboratoire de Biométrie et Biologie Evolutive · FRLaboratoire de Génétique Cellulaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate and compare the extent of LD in cattle, 1536 SNPs, mostly localized on BTA03, were detected in silico from available sequence data using two different methods and genotyped on samples from 14 distinct breeds originating from Europe and Africa. Only 696 SNPs could be validated, confirming the importance of trace-quality information for the in silico detection. Most of the validated SNPs were informative in several breeds and were used for a detailed description of their genetic structure and relationships. Results obtained were in agreement with previous studies performed on microsatellite markers and using larger samples. In addition, the majority of the validated SNPs could be mapped precisely, reaching an average density of one marker every 311 kb. This allowed us to analyze the extent of LD in the different breeds. Decrease of LD with physical distance across breeds revealed footprints of ancestral LD at short distances (<10 kb). As suggested by the haplotype block structure, these ancestral blocks are organized, within a breed, into larger blocks of a few hundred kilobases. In practice, such a structure similar to that already reported in dogs makes it possible to develop a chip of <300,000 SNPs, which should be efficient for mapping purposes in most cattle breeds.

Indexed as

HaplotypesLinkage DisequilibriumPolymorphism, Single NucleotideAfricaAnimalsBreedingCattleChromosome MappingComputational BiologyEuropeGenotypeMicrosatellite Repeats

Identifiers

PMID17720924
PMCPMC2034613
OpenAlexW2099232387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.