Evidence map›Paper›PMID 17720734›Full record

ArticleBiophysical journal2007

Time and length scales of autocrine signals in three dimensions.

Mathieu Coppey, Alexander M Berezhkovskii, Stuart C Sealfon, Stanislav Y Shvartsman

Abstract read
In one paragraph

Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Spatially structured inflammatory response in the presence of a uniform stimulus.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A simple model for assessment of anti-toxin antibodies.BioMed research international · 2013
    Article
  15. A reaction-diffusion model of the receptor-toxin-antibody interaction.Theoretical biology & medical modelling · 2011
    Article
  16. Article
  17. Article
  18. Article
  19. Antiviral-activated dendritic cells: a paracrine-induced response state.Journal of immunology (Baltimore, Md. : 1950) · 2008
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mathieu CoppeyDepartment of Chemical Engineering and Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.
Alexander M Berezhkovskii
Stuart C Sealfon
Stanislav Y Shvartsman

Funding

Modeling Immunity for BiodefenseN01AI50021 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · 2008 to 2010
$6.7M
STUDIES IN MATHEMATICS AND STATISTICSZ01CT000024 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI WEISS, GEORGE H · 1985 to 2008
$408k
Intramural NIH HHSNIAID NIH HHS N01 AI050021NIAID NIH HHS N01 AI 50021
6 · The paper itself

Abstract

A model of autocrine signaling in cultures of suspended cells is developed on the basis of the effective medium approximation. The fraction of autocrine ligands, the mean and distribution of distances traveled by paracrine ligands before binding, as well as the mean and distribution of the ligand lifetime are derived. Interferon signaling by dendritic immune cells is considered as an illustration.

Indexed as

Models, BiologicalAutocrine CommunicationBiophysical PhenomenaBiophysicsCells, CulturedDendritic CellsInterferonsLigandsParacrine CommunicationInterferonsLigands

Identifiers

PMID17720734
PMCPMC1959539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.