ArticleThe journal of physical chemistry. A2007
Photophysical properties of acene DCDHF fluorophores: long-wavelength single-molecule emitters designed for cellular imaging.
Article in The journal of physical chemistry. A, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 69 citations in OpenAlex.
- Exploring the excited state mechanisms of a viscosity-sensitive zeromethine merocyanine dye emitter.Chemical science · 2026Article
- Bright Solvatochromic Fluorophores With Dual Emission Enabled by a Donor-Engineering Strategy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- A Fluorogenic Reaction for Monitoring Cross-Coupling with Turn-On Ratio Greater than a Hundred Thousand.Chemical & biomedical imaging · 2026Article
- Evidence for a transfer-to-trap mechanism of fluorophore concentration quenching in lipid bilayers.Biophysical journal · 2024Article
- Photophysics of Fluorescent Contact Sensors Based on the Dicyanodihydrofuran Motif.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021Article
- A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores.The journal of physical chemistry letters · 2020Article
- Tunable Non-linear Refraction Properties and Ultrafast Excited State Dynamics of Dicyanomethylene Dihydrofuran Derivative.Frontiers in chemistry · 2020Article
- Unique Photophysical Behavior of Coumarin-Based Viscosity Probes during Molecular Self-Assembly.ACS omega · 2019Article
- Ultrafast Transient Absorption Spectra of Photoexcited YOYO-1 molecules call for additional investigations of their fluorescence quenching mechanism.Journal of photochemistry and photobiology. A, Chemistry · 2018Article
- Switchable Fluorophores for Single-Molecule Localization Microscopy.Chemical reviews · 2018Review
- Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.Royal Society open science · 2018Article
- Push-pull dioxaborine as fluorescent molecular rotor: far-red fluorogenic probe for ligand-receptor interactions.Journal of materials chemistry. C · 2016Article
- Extending single-molecule microscopy using optical Fourier processing.The journal of physical chemistry. B · 2014Article
- A bisected pupil for studying single-molecule orientational dynamics and its application to three-dimensional super-resolution microscopy.Applied physics letters · 2014Article
- The role of molecular dipole orientation in single-molecule fluorescence microscopy and implications for super-resolution imaging.Chemphyschem : a European journal of chemical physics and physical chemistry · 2014Review
- The double-helix point spread function enables precise and accurate measurement of 3D single-molecule localization and orientation.Proceedings of SPIE--the International Society for Optical Engineering · 2013Article
- Simultaneous, accurate measurement of the 3D position and orientation of single molecules.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Azido push-pull fluorogens photoactivate to produce bright fluorescent labels.The journal of physical chemistry. B · 2010Article
- Phthalocyanine dimerization-based molecular beacons using near-IR fluorescence.Journal of the American Chemical Society · 2009Article
- Bright, Red Single-Molecule Emitters: Synthesis and Properties of Environmentally Sensitive Dicyanomethylenedihydrofuran (DCDHF) Fluorophores with Bisaromatic Conjugation.Chemistry of materials : a publication of the American Chemical Society · 2009Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
We report the solvatochromic, viscosity-sensitive, and single-molecule photophysics of the fluorophores DCDHF-N-6 and DCDHF-A-6. These molecules are members of the dicyanomethylenedihydrofuran (DCDHF) class of single-molecule emitters that contain an amine electron donor and a DCDHF acceptor linked by a conjugated unit; DCDHF-N-6 and DCDHF-A-6 have naphthalene- and anthracene-conjugated linkers, respectively. These molecules maintain the beneficial photophysics of the phenylene-linked DCDHF (i.e., photostability, emission wavelength dependence on solvent polarity, and quantum yield sensitivity to solvent viscosity), yet offer absorption and emission at longer wavelengths that are more appropriate for cellular imaging. We demonstrate that these new fluorophores are less photolabile in an aqueous environment than several other commonly used dyes (rhodamine 6G, Texas Red, and fluorescein). Finally, we image single copies of the acene DCDHFs diffusing in the plasma membrane of living cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.