Evidence map›Paper›PMID 17716883›Full record

ReviewCurrent opinion in immunology2007

Acceleration of allograft failure by cytomegalovirus.

Daniel N Streblow, Susan L Orloff, Jay A Nelson

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02973464 (The Strategy in the Prevention of Renal Post-transplant Cytomegalovirus Infection Among Chinese Population), which is not on this map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02973464 unknown statusnot on this mapstarted 2016, after this paper: background citation

The Strategy in the Prevention of Renal Post-transplant Cytomegalovirus Infection Among Chinese Population

TypeobservationalSponsorFirst Affiliated Hospital Xi'an Jiaotong UniversityRan2016 to 2019Enrolled450ConditionsRenal Transplant RecipientsArmsValganciclovir, Ganciclovir
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 127 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Chemokine Subversion by Human Herpesviruses.Journal of innate immunity · 2018
    Review
  20. Chemokines encoded by herpesviruses.Journal of leukocyte biology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daniel N StreblowMMI, OHSU, Portland, OR, United States.
Susan L Orloff
Jay A Nelson
Oregon Health & Science University · USPortland VA Medical Center · US

Funding

MOLECULAR ASPECTS OF CYTOMEGALOVIRUS LATENCYR01AI021640 · NIAID · UNIVERSITY OF GUELPH · PI Meaghan H Hancock · 1985 to 2026
$8.1M
Molecular Aspects of Cytomegalovirus LatencyR37AI021640 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI HANCOCK, MEAGHAN H · 2018 to 2024
$4.0M
CHEMOKINE RECEPTORS IN VASCULAR DISEASER01HL065754 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NELSON, JAY A · 2000 to 2007
$2.7M
Cellular Basis of CMV Accelerated VasculopathyR01HL071695 · NHLBI · OREGON HEALTH AND SCIENCE UNIVERSITY · PI NELSON, JAY A · 2002 to 2005
$1.5M
Mechanisms of CMV latency in accelerated vascular diseaseR01HL083194 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI STREBLOW, DANIEL N · 2006 to 2010
$1.5M
VIRAL CHEMOKINE RECEPTORS: TRANSPLANT VASCULAR SCLEROSISR01HL066238 · NHLBI · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ORLOFF, SUSAN L · 2001 to 2003
$793k
NHLBI NIH HHS HL083194NHLBI NIH HHS HL65754NHLBI NIH HHS HL 66238-01NHLBI NIH HHS HL71695NHLBI NIH HHS R01 HL065754NHLBI NIH HHS R01 HL066238NHLBI NIH HHS R01 HL071695NHLBI NIH HHS R01 HL083194NIAID NIH HHS AI21640NIAID NIH HHS R01 AI021640NIAID NIH HHS R37 AI021640
6 · The paper itself

Abstract

A number of human herpesviruses are important opportunistic pathogens that have been associated with increased morbidity and mortality in transplant recipients including human cytomegalovirus (HCMV), HHV6, HHV7, HHV8 as well as HSV-1, VZV. However, HCMV has been linked both epidemiologically and through the use of animal models to the acceleration of acute and chronic allograft rejection. This review will cover the pathophysiology, epidemiology, and mechanisms of CMV-associated disease in the setting of transplantation.

Indexed as

AnimalsCytokinesCytomegalovirus InfectionsGraft RejectionHumansCytokines

Identifiers

PMID17716883
PMCPMC3509935
OpenAlexW1991966640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.