ArticleArchives of disease in childhood2007
High prevalence of vitamin D deficiency in newborn infants of high-risk mothers.
Article in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00697294 (Vitamin D Status and Impact on Bone Mineralization in Human Milk Fed Hispanic and Caucasian Infants), which is not on this map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin D Status and Impact on Bone Mineralization in Human Milk Fed Hispanic and Caucasian Infants
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- The role of vitamin D in prevention OF COVID-19 and its severity: an umbrella review.Acta bio-medica : Atenei Parmensis · 2021Pooled it
- Pooled estimate of vitamin D deficiency among pregnant women in India: a systematic review and meta-analysis.Journal of health, population, and nutrition · 2021Pooled it
- Pooled it
- Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.PloS one · 2017Pooled it
- Global summary of maternal and newborn vitamin D status - a systematic review.Maternal & child nutrition · 2016Pooled it
- Maternal and neonatal 25-hydroxyvitamin D concentrations and school-age lung function, asthma and allergy. The Generation R Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Trial
- Comparison of two regimens of vitamin D supplementation for vitamin D-deficient neonates.Singapore medical journal · 2014Trial
- Article
- Influence of maternal socioeconomic deprivation and living environment on newborn bloodspot 25-hydroxyvitamin D levels.Frontiers in endocrinology · 2022Article
- Gut microbiota: Linking nutrition and perinatal depression.Frontiers in cellular and infection microbiology · 2022Review
- Vitamin D Deficiency Prevalence in Late Neonatal Hypocalcemia: A Multicenter StudyJournal of clinical research in pediatric endocrinology · 2021Article
- Serum 25 hydroxyvitamin D levels and affecting factors among preconception fertile women.BMC women's health · 2020Article
- Screening of vitamin D and calcium concentrations in neonates of mothers at high risk of vitamin D deficiency.BMC pediatrics · 2020Article
- Cord Blood Vitamin D Levels and Early Childhood Blood Pressure: The Healthy Start Study.Journal of the American Heart Association · 2019Article
- Vitamin D status of White pregnant women and infants at birth and 4 months in North West England: A cohort study.Maternal & child nutrition · 2018Article
- Comparative analysis of nutritional guidelines for vitamin D.Nature reviews. Endocrinology · 2017Review
- Autism spectrum disorder and low vitamin D at birth: a sibling control study.Molecular autism · 2015Article
- Vitamin D deficiency among native Dutch and first- and second-generation non-Western immigrants.European journal of pediatrics · 2014Article
- Obesity and Vitamin D Deficiency - Current Concepts on their Impact on Pregnancy.European endocrinology · 2013Review
- Impact of maternal vitamin D status during pregnancy on the prevalence of neonatal vitamin D deficiency.Pediatric reports · 2013Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the prevalence of vitamin D deficiency in newborn infants of mothers at risk of vitamin D deficiency because of dark skin or the wearing of concealing clothes (such as a veil) compared with a group presumed not to be at risk. A second aim was to correlate these newborn infants' vitamin D concentrations with biochemical parameters of vitamin D metabolism and bone turnover at birth.
designA prospective study conducted between April 2004 and February 2006 including women delivering during this period and their newborn infants.
settingThe outpatient clinic of the obstetrics department, Sint Franciscus Gasthuis, Rotterdam, the Netherlands. PATIENTS: Eighty seven newborn infants of healthy mothers with either dark skin and/or concealing clothing (risk group) or light skin (control group).
resultsWe found a significant difference in the prevalence of vitamin D deficiency (25-hydroxyvitamin D(3) <25 nmol/l) between newborn infants of mothers at risk and those of mothers in the control group (63.3% vs 15.8%; p<0.001). Mean alkaline phosphatase concentrations were significantly higher in the at risk group.
conclusionsNewborn infants of mothers with dark skin or wearing concealing clothes are at great risk of vitamin D deficiency at birth. The clinical implications are unknown. Further research is necessary to determine the long-term consequences of maternal and neonatal vitamin D deficiency so that guidelines on vitamin D supplementation during pregnancy can be issued.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.