ArticleJournal of virology2007
A human lung carcinoma cell line supports efficient measles virus growth and syncytium formation via a SLAM- and CD46-independent mechanism.
Article in Journal of virology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Peste des petits ruminants in Africa: Meta-analysis of the virus isolation in molecular epidemiology studies.The Onderstepoort journal of veterinary research · 2019Pooled it
- Probenecid Treatment Inhibits Replication of the Edmonston Measles Virus Strain in Vero Cells.Viruses · 2025Article
- Article
- Short-Stalk Isoforms of CADM1 and CADM2 Trigger Neuropathogenic Measles Virus-Mediated Membrane Fusion by Interacting with the Viral Hemagglutinin.Journal of virology · 2022Article
- Marine Morbilliviruses: Diversity and Interaction with Signaling Lymphocyte Activation Molecules.Viruses · 2019Review
- Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V.PLoS pathogens · 2019Article
- The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein.Viruses · 2016Review
- A scalable method to concentrate lentiviral vectors pseudotyped with measles virus glycoproteins.Gene therapy · 2015Article
- Measles vaccine strains for virotherapy of non-small-cell lung carcinoma.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2014Article
- Measles virus nonstructural C protein modulates viral RNA polymerase activity by interacting with host protein SHCBP1.Journal of virology · 2013Article
- Measles virus infection of epithelial cells in the macaque upper respiratory tract is mediated by subepithelial immune cells.Journal of virology · 2013Article
- Mutant fusion proteins with enhanced fusion activity promote measles virus spread in human neuronal cells and brains of suckling hamsters.Journal of virology · 2013Article
- The V protein of canine distemper virus is required for virus replication in human epithelial cells.PloS one · 2013Article
- Functional and structural characterization of neutralizing epitopes of measles virus hemagglutinin protein.Journal of virology · 2013Article
- Wild-type measles virus with the hemagglutinin protein of the edmonston vaccine strain retains wild-type tropism in macaques.Journal of virology · 2012Article
- Morbillivirus receptors and tropism: multiple pathways for infection.Frontiers in microbiology · 2012Article
- Canine distemper virus infects canine keratinocytes and immune cells by using overlapping and distinct regions located on one side of the attachment protein.Journal of virology · 2011Article
- The SI strain of measles virus derived from a patient with subacute sclerosing panencephalitis possesses typical genome alterations and unique amino acid changes that modulate receptor specificity and reduce membrane fusion activity.Journal of virology · 2011Article
- Expression of the Sendai (murine parainfluenza) virus C protein alleviates restriction of measles virus growth in mouse cells.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus.PLoS pathogens · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measles virus (MV) propagates mainly in lymphoid organs throughout the body and produces syncytia by using signaling lymphocyte activation molecule (SLAM) as a receptor. MV also spreads in SLAM-negative epithelial tissues by unknown mechanisms. Ubiquitously expressed CD46 functions as another receptor for vaccine strains of MV but not for wild-type strains. We here show that MV grows and produces syncytia efficiently in a human lung adenocarcinoma cell line via a SLAM- and CD46-independent mechanism using a novel receptor-binding site on the hemagglutinin protein. This infection model could advance our understanding of MV infection of SLAM-negative epithelial cells and tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.