ArticleDie Naturwissenschaften2008
Measurement of flow speed in the channels of novel threadlike structures on the surfaces of mammalian organs.
Article in Die Naturwissenschaften, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Visualizing the Peripheral Primo Vascular System in Mice Skin by Using the Polymer Mercox.Journal of pharmacopuncture · 2015Article
- Essential Experimental Methods for Identifying Bonghan Systems as a Basis for Korean Medicine: Focusing on Visual Materials from Original Papers and Modern Outcomes.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques.Beilstein journal of nanotechnology · 2015Review
- Review and Comment on the Relationship between Primo Vascular System and Meridians.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Toward a theory of the primo vascular system: a hypothetical circulatory system at the subcellular level.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- 50 years of bong-han theory and 10 years of primo vascular system.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Gross morphological features of the organ surface primo-vascular system revealed by hemacolor staining.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Observation of a long primo vessel in a lymph vessel from the inguinal node of a rabbit.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- The primo vascular structures alongside nervous system: its discovery and functional limitation.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Differentiating blood, lymph, and primo vessels by residual time characteristic of fluorescent nanoparticles in a tumor model.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Primo vascular system accompanying a blood vessel from tumor tissue and a method to distinguish it from the blood or the lymph system.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Evidence for an additional metastatic route: in vivo imaging of cancer cells in the primo-vascular system around tumors and organs.Molecular imaging and biology · 2011Article
- TEA-sensitive currents contribute to membrane potential of organ surface primo-node cells in rats.The Journal of membrane biology · 2011Article
- Article
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Authors and funding
8 authors.
Funding
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Abstract
There have been several reports on novel threadlike structures (NTSs) on the surfaces of the internal organs of rats and rabbits since their first observation by Bonghan Kim in 1963. To confirm this novel circulatory function, it is necessary to observe the flow of liquid through the NTS as well as the structurally corroborating channels in the NTS. In this article, we report on the measurement of the flow speed of Alcian blue solution in the NTSs on the organ surfaces of rabbits, and we present electron microscopic images depicting the cribrous cross-section with channels. The speed was measured as 0.3 +/- 0.1 mm/s, and the flow distance was up to 12 cm. The flow was unidirectional, and the phase contrast microscopic images showed that the NTSs were strongly stained with Alcian blue. The ultrastructure of the NTSs revealed by cryo-scanning electron microscopy and high-voltage electron microscopy showed that (1) there were cell-like bodies and globular clumps of matter inside the sinus of the channel with thin strands of segregated zones which is a microscopic evidence of the liquid flow, (2) the sinuses have wall structures surrounded with extracellular matrices of collagenous fibers, and (3) there exists a cribriform structure of sinuses. To understand the mechanism for the circulation, a quantitative analysis of the flow speed has been undertaken applying a simplified windkessel model. In this analysis, it was shown that the liquid flow through the NTSs could be due to peristaltic motion of the NTS itself.
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