ArticleParasitology research2007
First report of multiple drug resistance in trichostrongyles affecting sheep under field conditions in Italy.
Article in Parasitology research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- The efficacy of trichlorphon and naphthalophos against multiple anthelmintic-resistant nematodes of naturally infected sheep in Argentina.Parasitology research · 2011Trial
- Pellets enriched with healthy hay and quebracho are not sufficient to control gastrointestinal nematodes in meat sheep commercial flocks.Parasitology · 2024Article
- Prevalence of Helminths in Small Ruminant Farms and Evaluation of Control Practices Used to Counter Anthelmintic Resistance in Southern Italy.Pathogens (Basel, Switzerland) · 2024Article
- Effect of pomegranate (Frontiers in veterinary science · 2024Article
- Control of gastrointestinal helminths in small ruminants to prevent anthelmintic resistance: the Italian experience.Parasitology · 2023Review
- Most common inappropriate drug usage factors in anthelmintic treatment on sheep farms in Latvia.Veterinary world · 2022Article
- Parasitofauna and current status of anthelmintic resistance in Latvian sheep farms.Veterinary world · 2022Article
- Traditional Latvian herbal medicinal plants used to treat parasite infections of small ruminants: A review.Veterinary world · 2021Review
- Survey on Endoparasites of Dairy Goats in North-Eastern Italy Using a Farm-Tailored Monitoring Approach.Veterinary sciences · 2021Article
- The threat of reduced efficacy of anthelmintics against gastrointestinal nematodes in sheep from an area considered anthelmintic resistance-free.Parasites & vectors · 2020Article
- Anthelmintic resistance in gastrointestinal nematodes in sheep raised under mountain farming conditions in Northern Italy.Veterinary record open · 2019Article
- Article
- A comparison of two different anthelmintic treatment regimens against natural gastrointestinal nematode infections on two Lithuanian sheep farms.Acta veterinaria Scandinavica · 2017Article
- Benzimidazole resistance survey for Haemonchus, Teladorsagia and Trichostrongylus in three European countries using pyrosequencing including the development of new assays for Trichostrongylus.International journal for parasitology. Drugs and drug resistance · 2016Article
- Effectiveness of Ivermectin and Albendazole against Haemonchus contortus in Sheep in West Java, Indonesia.Tropical life sciences research · 2016Article
- Prevalence of anthelmintic resistance on Lithuanian sheep farms assessed by in vitro methods.Acta veterinaria Scandinavica · 2015Article
- Gastrointestinal nematodes of dairy goats, anthelmintic resistance and practices of parasite control in Northern Italy.BMC veterinary research · 2014Article
- Is the micro-agar larval development test reliable enough to detect ivermectin resistance?Parasitology research · 2012Article
- Prevalence of anthelmintic resistance in gastrointestinal nematodes of sheep and goats in Norway.Parasitology research · 2012Article
- Characterization of a multidrug resistant Teladorsagia circumcincta isolate from Spain.Parasitology research · 2012Article
Corrections and comments
- Erratum issuedDosage error in article text
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug resistance in sheep gastrointestinal trichostrongyles is a cosmopolitan major constraint to small ruminant production. Despite reports that anthelmintic drug resistance has become common, there are limited information on the presence of drug resistance in Italy. The purpose of this study was to determine the effect of four anthelmintics to control infection in sheep in central Italy. Fifty sheep with fecal egg counts (FEC) > or =150 eggs per gram were selected on each of three farms (n = 150 total sheep) which were randomly allocated to one of five groups. Groups were treated with febantel, levamisole, ivermectin, or moxidectin while the fifth group acted as the control group. A FEC reduction test (FECRT) was conducted on each animal and the mean FEC of each treatment group was compared to that of the control group within farm. Resistance was declared when percentage reduction (R) <95% and the lower 95% confidence interval was <90%. Levamisole (mean R = 89%) resistance was found on all farms and ivermectin (mean R = 93%) resistance was found on two of the three farms. Posttreatment larval cultures showed the presence of Teladorsagia (Ostertagia) circumcincta and Trichostrongylus spp. larvae. Febantel (mean R = 96%) and moxidectin (mean R = 100%) remained effective. This study suggests that drug resistance in sheep gastrointestinal trichostrongyles is present in central Italy and a potential problem which would justify a broader nationwide geographical investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.