ArticleGenome research2007
A new approach to estimate parameters of speciation models with application to apes.
Article in Genome research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.
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Who cites it
106 citing papers in PubMed, 251 citations in OpenAlex.
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- A segmental duplication-mediated deletion leads to neocentromere formation in orangutans.bioRxiv : the preprint server for biology · 2026Article
- Inference of Coalescence Times and Variant Ages Using Convolutional Neural Networks.Molecular biology and evolution · 2023Article
- Ghost admixture in eastern gorillas.Nature ecology & evolution · 2023Article
- Ten years of demographic modelling of divergence and speciation in the sea.Evolutionary applications · 2023Article
- Graph-based algorithms for Laplace transformed coalescence time distributions.PLoS computational biology · 2022Article
- Population dynamics and genetic connectivity in recent chimpanzee history.Cell genomics · 2022Article
- Estimating bonobo (Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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- A brief history and popularity of methods and tools used to estimate micro-evolutionary forces.Ecology and evolution · 2021Review
- Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution.BMC evolutionary biology · 2020Article
- Efficiently Summarizing Relationships in Large Samples: A General Duality Between Statistics of Genealogies and Genomes.Genetics · 2020Article
- Adaptive divergence in shell morphology in an ongoing gastropod radiation from Lake Malawi.BMC evolutionary biology · 2020Article
- Recent advances in Bayesian inference of isolation-with-migration models.Genomics & informatics · 2019Article
- Detection of Shared Balancing Selection in the Absence of Trans-Species Polymorphism.Molecular biology and evolution · 2019Article
- Phylogeny Estimation by Integration over Isolation with Migration Models.Molecular biology and evolution · 2018Article
- ABLE: blockwise site frequency spectra for inferring complex population histories and recombination.Genome biology · 2018Article
- Ancestral polymorphisms explain the role of chromosomal inversions in speciation.PLoS genetics · 2018Article
- Article
- Modeling the Multiple Facets of Speciation-with-Gene-Flow toward Inferring the Divergence History of Lake Whitefish Species Pairs (Coregonus clupeaformis).Genome biology and evolution · 2017Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
How populations diverge and give rise to distinct species remains a fundamental question in evolutionary biology, with important implications for a wide range of fields, from conservation genetics to human evolution. A promising approach is to estimate parameters of simple speciation models using polymorphism data from multiple loci. Existing methods, however, make a number of assumptions that severely limit their applicability, notably, no gene flow after the populations split and no intralocus recombination. To overcome these limitations, we developed a new Markov chain Monte Carlo method to estimate parameters of an isolation-migration model. The approach uses summaries of polymorphism data at multiple loci surveyed in a pair of diverging populations or closely related species and, importantly, allows for intralocus recombination. To illustrate its potential, we applied it to extensive polymorphism data from populations and species of apes, whose demographic histories are largely unknown. The isolation-migration model appears to provide a reasonable fit to the data. It suggests that the two chimpanzee species became reproductively isolated in allopatry approximately 850 Kya, while Western and Central chimpanzee populations split approximately 440 Kya but continued to exchange migrants. Similarly, Eastern and Western gorillas and Sumatran and Bornean orangutans appear to have experienced gene flow since their splits approximately 90 and over 250 Kya, respectively.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.