ArticleEmergency medicine journal : EMJ2007
Validation of a diagnostic reminder system in emergency medicine: a multi-centre study.
Article in Emergency medicine journal : EMJ, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic Review.Journal of medical Internet research · 2021Pooled it
- The Effectiveness of Electronic Differential Diagnoses (DDX) Generators: A Systematic Review and Meta-Analysis.PloS one · 2016Pooled it
- Comparison of Two Symptom Checkers (Ada and Symptoma) in the Emergency Department: Randomized, Crossover, Head-to-Head, Double-Blinded Study.Journal of medical Internet research · 2024Trial
- Effects of a Differential Diagnosis List of Artificial Intelligence on Differential Diagnoses by Physicians: An Exploratory Analysis of Data from a Randomized Controlled Study.International journal of environmental research and public health · 2021Trial
- Early diagnostic suggestions improve accuracy of GPs: a randomised controlled trial using computer-simulated patients.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Trial
- Feasibility of Pediatric Diagnostic Quality Measurement in All United States Hospitals.Annals of emergency medicine · 2026Article
- Cracking the code: a head-to-head comparison of expert clinicians and artificial intelligence in diagnosing rare diseases.Orphanet journal of rare diseases · 2025Article
- Large Language Models in the Diagnosis of Hand and Peripheral Nerve Injuries: An Evaluation of ChatGPT and the Isabel Differential Diagnosis Generator.Journal of hand surgery global online · 2024Article
- Emergency department use of an electronic differential diagnosis generator in the evaluation of critically ill patients.Internal and emergency medicine · 2024Observational
- Diagnostic Errors in Hospitalized Adults Who Died or Were Transferred to Intensive Care.JAMA internal medicine · 2024Article
- Evaluation of medical decision support systems (DDX generators) using real medical cases of varying complexity and origin.BMC medical informatics and decision making · 2022Article
- Article
- The global burden of diagnostic errors in primary care.BMJ quality & safety · 2017Review
- Characteristics of patients contacting a center for undiagnosed and rare diseases.Orphanet journal of rare diseases · 2016Article
- Developing checklists to prevent diagnostic error in Emergency Room settings.Diagnosis (Berlin, Germany) · 2014Article
- Use of health information technology to reduce diagnostic errors.BMJ quality & safety · 2013Review
- Application of appropriateness criteria for hospitalization in COPD exacerbation.Internal and emergency medicine · 2013Article
- The utility of an online diagnostic decision support system (Isabel) in general practice: a process evaluation.JRSM short reports · 2013Article
- Modeling paradigms for medical diagnostic decision support: a survey and future directions.Journal of medical systems · 2012Review
- Differential diagnosis generators: an evaluation of currently available computer programs.Journal of general internal medicine · 2012Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiagnostic error is a significant problem in emergency medicine, where initial clinical assessment and decision making is often based on incomplete clinical information. Traditional computerised diagnostic systems have been of limited use in the acute setting, mainly due to the need for lengthy system consultation. We evaluated a novel web-based reminder system, which provides rapid diagnostic advice to users based on free text search terms.
methodsClinical data collected from patients presenting to three emergency departments with acute medical problems were entered into the diagnostic system. The displayed results were assessed against the final discharge diagnoses for patients who were admitted to hospital (diagnostic accuracy) and against a set of "appropriate" diagnoses for each case provided by an expert panel (potential utility).
resultsData were collected from 594 patients (53.4% of screened attendances). Mean age was 49.4 years (95% CI 47.7 to 51.1) and the majority had significant past illnesses. Most were assessed first by junior doctors (70%) and 266/594 (44.6%) were admitted to hospital. Overall, the diagnostic system displayed the final discharge diagnosis in 95% of inpatients and 90% of "must-not-miss" diagnoses suggested by the expert panel. The discharge diagnosis appeared within the first 10 suggestions in 78% of cases.
conclusionsThe Isabel diagnostic aid has been shown to be of potential use in reminding junior doctors of key diagnoses in the emergency department. The effects of its widespread use on decision making and diagnostic error can be clarified by evaluating its impact on routine clinical decision making.
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