ArticleJournal of fluorescence2007
Acidichromism and ionochromism of luteolin and apigenin, the main components of the naturally occurring yellow weld: a spectrophotometric and fluorimetric study.
Article in Journal of fluorescence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 125 citations in OpenAlex.
- Photoacidity and ESIPT in luteolin: acidity-vibrational frequency relationships across electronic states.RSC advances · 2026Article
- 3D-Fluorescence Supported by Optical Reflectance and Raman Spectroscopy for the Analysis of Natural Dyes in Ancient Textiles: Potential and Limitations.Journal of fluorescence · 2025Article
- Synthesis of Mo, N-doped carbon dots for the fluorescence detection of CrRSC advances · 2025Article
- Luteolin in Inflammatory Bowel Disease and Colorectal Cancer: A Disease Continuum Perspective.Current issues in molecular biology · 2025Review
- Comparative Study of Fluorescence Emission of Fisetin, Luteolin and Quercetin Powders and Solutions: Further Evidence of the ESIPT Process.Biosensors · 2024Article
- Oxygen mediated oxidative couplings of flavones in alkaline water.Nature communications · 2022Article
- Synthesis of Vapochromic Dyes Having Sensing Properties for Vapor Phase of Organic Solvents Used in Semiconductor Manufacturing Processes and Their Application to Textile-Based Sensors.Sensors (Basel, Switzerland) · 2022Article
- Nitrogen-doped graphene-poly(hydroxymethylated-3,4-ethylenedioxythiophene) nanocomposite electrochemical sensor for ultrasensitive determination of luteolin.RSC advances · 2022Article
- A Review on Coordination Properties of Al(III) and Fe(III) toward Natural Antioxidant Molecules: Experimental and Theoretical Insights.Molecules (Basel, Switzerland) · 2021Review
- Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: involvement of cell line-specific apoptotic mechanisms.International journal of cancer · 2012Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Luteolin and apigenin, extracted from Reseda luteola L., were spectrophotometrically and fluorimetrically studied. The spectra were investigated as a function of pH in methanol/water solutions (1/2, v/v) in the 2-12 pH range. The absorption spectra markedly shifted to the red by increasing the pH. Three acid-base dissociation steps were detected for luteolin (pK (a) = 6.9; 8.6; 10.3) and two for apigenin (pK (a) = 6.6; 9.3). Fluorescence emission was very weak or undetectable (Phi (F) < 10(-4)) in acidic solution, but increased in intensity with increasing the pH. Both molecules exhibited a great propensity towards complex formation with metal ions, with association constants on the order of 10(5)-10(7) for the first complexation step; in the presence of excess Al(3+) ions, multiple equilibria were detected. A marked fluorescence enhancement was observed upon complexation with Al(3+) ions (Phi (F) approximately 1 for luteolin and approximately 10(-2) for apigenin).
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Registered trials
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